Clinical improvement of lead poisoning following extraction of retained bullet fragments

Surgery Case Reports Pub Date : 2025-03-01 Epub Date: 2025-02-03 DOI:10.1016/j.sycrs.2025.100092
Ashley Wittmer , Emilia Coffey , Francis Buzad
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Abstract

Lead poisoning presents with variable symptoms, ranging from asymptomatic cases to significant neurological deficits. This report describes a 39-year-old male with chronic symptoms, including abdominal pain, back pain, and mood changes, 12 years after sustaining a gunshot wound to the thigh with retained bullet fragments. Preoperative serum lead levels were mildly elevated at 5.3 µg/dL. Surgical removal of major bullet fragments was performed with fluoroscopic guidance, minimizing tissue trauma. Postoperatively, the patient experienced substantial improvement in symptoms suspected to be caused by lead exposure, including resolution of abdominal pain and fatigue. Serum lead levels gradually declined to 4.4 µg/dL at seven months post-surgery. This case demonstrates the potential benefits of surgical intervention for retained lead fragments when symptoms are suspected to result from lead toxicity. The intervention led to improvement of the patient’s symptoms and reduced serum lead levels. Further research is warranted to establish guidelines for the optimal management of retained bullet fragments, balancing surgical risks with potential clinical benefits.
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子弹残片取出后铅中毒的临床改善
铅中毒表现为各种症状,从无症状病例到严重的神经功能缺损。本报告描述了一名患有慢性症状的39岁男性,包括腹痛、背痛和情绪变化,12年前大腿中枪,子弹碎片残留。术前血清铅含量轻度升高,为5.3 µg/dL。手术切除主要的子弹碎片是在透视引导下进行的,最大限度地减少了组织损伤。术后,患者疑似铅暴露引起的症状明显改善,包括腹痛和疲劳的缓解。术后7个月血清铅含量逐渐下降至4.4 µg/dL。该病例表明,当怀疑症状是由铅中毒引起时,手术干预对残留铅碎片的潜在益处。干预措施改善了患者的症状,降低了血清铅水平。进一步的研究是必要的,以建立指导方针的最佳管理保留的子弹碎片,平衡手术风险和潜在的临床效益。
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