Partnership and marriage and risk of type 2 diabetes: a narrative review

IF 10.2 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetologia Pub Date : 2025-02-07 DOI:10.1007/s00125-025-06360-3
Bernd Kowall, Wolfgang Rathmann
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Abstract

In this review, we discuss how partnership and marriage influence cardiometabolic risk factors and risk of type 2 diabetes, and how couple-based approaches to type 2 diabetes prevention might complement individual-focused prevention efforts. There is some evidence that being married per se has a small positive effect on type 2 diabetes risk. Moreover, there is spousal concordance for many type 2 diabetes risk factors due to assortative mating and convergence during partnership, with weak to moderate correlations found for anthropometric measures, blood pressure, lipid concentrations, smoking, alcohol consumption and physical activity level. A meta-analysis shows that people have a higher risk of type 2 diabetes if their spouse has diabetes (OR 1.72, 95% CI 1.47, 2.02). However, despite some evidence, there is still a lack of research on similar associations in relation to progression to type 2 diabetes and diabetes complications. Several studies have suggested that behaviour changes, for example smoking cessation or weight loss, in one partner increase the likelihood that the other partner will make the same changes. Subsequent studies of couple-based interventions that focus on both partners have shown that people are more likely to adhere to a diabetes prevention programme if their partners are also involved in the programme. However, the effect of the quality of marriage on the outcome of an intervention is still unclear. Couple-based interventions are promising, but there is a lack of RCTs comparing couple-based interventions with individual-centred interventions.

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伴侣关系、婚姻与2型糖尿病风险:一项叙述性综述
在这篇综述中,我们讨论了伴侣关系和婚姻如何影响心脏代谢危险因素和2型糖尿病的风险,以及以夫妻为基础的2型糖尿病预防方法如何补充以个人为中心的预防工作。有一些证据表明,结婚本身对2型糖尿病的风险有很小的积极影响。此外,由于选择性交配和伴侣关系中的趋同,许多2型糖尿病风险因素存在配偶一致性,人体测量值、血压、脂质浓度、吸烟、饮酒和身体活动水平之间存在弱至中度相关性。一项荟萃分析显示,配偶患有糖尿病的人患2型糖尿病的风险更高(OR 1.72, 95% CI 1.47, 2.02)。然而,尽管有一些证据,但仍然缺乏与2型糖尿病进展和糖尿病并发症相关的类似关联的研究。几项研究表明,一方的行为改变,例如戒烟或减肥,会增加另一方做出同样改变的可能性。随后针对夫妻双方的干预研究表明,如果他们的伴侣也参与糖尿病预防规划,人们更有可能坚持该规划。然而,婚姻质量对干预结果的影响尚不清楚。以夫妇为基础的干预措施是有希望的,但缺乏比较以夫妇为基础的干预措施与以个人为中心的干预措施的随机对照试验。图形抽象
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来源期刊
Diabetologia
Diabetologia 医学-内分泌学与代谢
CiteScore
18.10
自引率
2.40%
发文量
193
审稿时长
1 months
期刊介绍: Diabetologia, the authoritative journal dedicated to diabetes research, holds high visibility through society membership, libraries, and social media. As the official journal of the European Association for the Study of Diabetes, it is ranked in the top quartile of the 2019 JCR Impact Factors in the Endocrinology & Metabolism category. The journal boasts dedicated and expert editorial teams committed to supporting authors throughout the peer review process.
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