Comparative Study of Different Irrigation Protocols in Endodontic Treatment.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-10-29 DOI:10.4103/jpbs.jpbs_841_24
Midhun Paul, Rekha V Ravi, Chintu Sundaresan, Dinesh G Kamath, Gargi Yumnam, Nada M Ibrahim
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Abstract

Background: Irrigation is ideal in endodontic treatment as it helps in the removal of bacteria, softening of the organic structure, and then evacuation of debris in the root canal.

Materials and methods: This in vitro study involved 60 extracted single-rooted human teeth, randomly assigned to three groups (n = 20) based on the irrigation protocol used: The three tested products were Group A, sodium hypochlorite 5. 25%; Group B, Chlorhexidine 2%; and finally, Group C, EDTA 17%. Both groups rated equal in terms of the root canal preparation they were put through. A microbiological technique, debris, and smear layer removal were employed to determine irrigation efficacy, and scanning electron microscopy (SEM) was used on the extracted roots. In this study, the analysis of variance and post hoc tests were used with a predetermined alpha level of (0.05).

Results: Comparing all the groups, Group A exhibited the best performance with Group B being the second best as seen with the mean log reduction of the bacterial load being 5. With 4.77 (±0. 54), Group A had the highest mean log reduction, while Group B recorded a mean log reduction of 2 (±0. 4). 54 (±0. 36) and Group C had a mean log reduction of 3. 9 (±0. 6). The SEM analysis for Group A was as follows: the cleanliness of samples was found to 85% in contrast to 70% in Group B and 50% in Group C (P < 0.05).

Conclusion: Sodium hypochlorite 5. Twenty five percent was found to be the most effective Results showed that 25% is the most effective irrigation protocol in lowering bacterial count as well as in flushing out debris and smear layer from root canal.

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不同灌洗方法在牙髓治疗中的比较研究。
背景:灌洗在根管治疗中是理想的,因为它有助于去除细菌,软化有机结构,然后排出根管内的碎片。材料与方法:本体外研究选取60颗拔除的人单根牙齿,根据所采用的冲洗方案随机分为3组(n = 20): A组次氯酸钠5。25%;B组:氯己定2%;最后是C组,EDTA 17%。两组在根管准备方面的评分相同。采用微生物技术、碎屑和涂抹层去除来确定灌溉效果,并对提取的根进行扫描电子显微镜(SEM)观察。在本研究中,采用方差分析和事后检验,预设α水平为(0.05)。结果:与所有组相比,A组表现最好,B组次之,细菌负荷平均对数减少5。4.77(±0。A组的平均对数降低率最高,而B组的平均对数降低率为2(±0。4.54(±0.54)36), C组平均对数降低3。9(±0。6). A组样品的SEM分析结果如下:样品清洁度为85%,B组为70%,C组为50% (P < 0.05)。结论:次氯酸钠;结果表明,25%的灌溉方案在降低细菌数量以及冲洗根管内的碎屑和涂片层方面是最有效的。
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