Incidence and Pathological Analysis of Parasitic Infections in Underserved Communities.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-09-11 DOI:10.4103/jpbs.jpbs_705_24
Abhishek Raval, Manan Jadav, Ritesh Gohil, Maulik Vora
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Abstract

Background: Parasitic infections remain a significant public health concern, particularly in underserved communities where access to healthcare and sanitation is limited. This study aims to investigate the incidence and pathological characteristics of parasitic infections in such communities, providing insights into the prevalence and impact of these infections on public health.

Materials and methods: A cross-sectional study was conducted in underserved communities over a period of one year. A total of 500 participants were randomly selected and screened for parasitic infections through stool and blood samples. The samples were analyzed using microscopy and polymerase chain reaction (PCR) techniques to identify and quantify parasitic species. Pathological examinations were performed to assess the impact of infections on host tissues.

Results: The incidence of parasitic infections was found to be 35% among the study population. The most common parasites identified were Ascaris lumbricoides (40%), Giardia lamblia (25%), and Entamoeba histolytica (20%). Pathological analysis revealed that Ascaris lumbricoides caused significant intestinal inflammation in 30% of infected individuals, while Giardia lamblia was associated with malabsorption syndrome in 15% of cases. Entamoeba histolytica was linked to liver abscesses in 10% of the infected participants.

Conclusion: Parasitic infections are highly prevalent in underserved communities, with significant pathological impacts on affected individuals.

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服务不足社区寄生虫感染的发病率和病理分析。
背景:寄生虫感染仍然是一个重大的公共卫生问题,特别是在获得医疗保健和卫生设施有限的服务不足的社区。本研究旨在调查这些社区寄生虫感染的发病率和病理特征,为这些感染的流行及其对公共卫生的影响提供见解。材料和方法:在服务不足的社区进行了为期一年的横断面研究。共有500名参与者被随机选择,并通过粪便和血液样本进行寄生虫感染筛查。利用显微镜和聚合酶链反应(PCR)技术对样品进行鉴定和定量。病理检查评估感染对宿主组织的影响。结果:研究人群中寄生虫感染的发生率为35%。最常见的寄生虫是类蚓蛔虫(40%)、兰第鞭毛虫(25%)和溶组织内阿米巴(20%)。病理分析显示,30%的感染个体中蛔虫引起明显的肠道炎症,而15%的感染病例中伴有兰氏贾第鞭毛虫吸收不良综合征。溶组织内阿米巴在10%的感染者中与肝脓肿有关。结论:寄生虫感染在服务水平低下的社区高度流行,对感染个体有明显的病理影响。
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