Si-Yang Huang, Pan-Pan Zhang, Meng-Xia Yan, Yang-Yang Wang, Mei-Lan Yu, De-Kai Wang, Bo Yang
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引用次数: 0
Abstract
A phytochemical study of the leaves of Cyclocarya paliurus led to the discovery of five naphthalene derivatives (1-5) and two diarylheptanoids (6-7), among which compounds 1 and 6 are new natural products. The structural elucidation of these new compounds was achieved through an in-depth examination of spectroscopic data, including NMR, MS, and IR. Their absolute configurations were established using electronic circular dichroism (ECD) calculation and dimolybdenum tetraacetate-induced circular dichroism CD (ICD) experiments. Notably, compound 7 exhibited inhibitory activity against α-glucosidase, demonstrating an IC50 value of 14.5 ± 3.3 µM.
期刊介绍:
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.