Characterization of Aeromonas Strains Isolated from Adult Patients with Diarrhea and Aquatic Environments - Beijing Municipality, China, 2016-2022.

IF 4.3 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 中国疾病预防控制中心周报 Pub Date : 2025-01-24 DOI:10.46234/ccdcw2025.019

Ying Li, Keyi Yu, Xiaoli Du, Yuwei Liu, Aixia Yan, Miao Wang, Ying Kang, Shoufei Li, Yuanyuan Wang, Luotong Wang, Shengtian Liu, Tao Peng, Jun Li, Duochun Wang, Zhenzhou Huang

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Abstract

Introduction: Aeromonas is widely distributed in aquatic environments. This study describes the pathogenic characteristics of Aeromonas isolated from adult diarrhea patients and aquatic environments in Beijing, China.

Methods: Aeromonas isolates from patients with diarrhea and river water samples were assessed using whole-genome sequencing (WGS) and antibiotic resistance profiling.

Results: In total, 38 Aeromonas isolates were collected. Among these, 13 isolates were from patients with common clinical symptoms, including diarrhea, abdominal pain, and nausea. Four of 13 Aeromonas-positive patients were co-infected with other intestinal pathogens. Patient-derived Aeromonas isolates showed high resistance to ampicillin, ampicillin-sulbactam, nalidixic acid, and tetracycline, whereas water-derived isolates showed high resistance to ampicillin, ampicillin-sulbactam, and nalidixic acid. Phylogenetic analysis revealed seven independent branches, without significant clustering among patient- and water-derived isolates.

Conclusions: This study provides valuable insights into the prevalence and characteristics of Aeromonas. The intertwined distribution of patient- and water-derived isolates in the phylogenetic tree deserves attention.

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