Meckel's diverticulum with ectopic pancreatic and epididymal tissue in a newborn infant

Sana Ahuja, Shaivy Malik, Sufian Zaheer
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Abstract

Introduction and importance

Meckel's diverticulum is a congenital anomaly affecting about 2 % of the population due to incomplete omphalomesenteric duct closure during fetal development. While often asymptomatic, it can cause complications like obstruction and bleeding. Ectopic tissue within the diverticulum, such as gastric and pancreatic tissue, is reported. This report presents a unique case of ectopic pancreatic and epididymal tissue in a newborn's Meckel's diverticulum, emphasizing the significance of histopathological examination.

Case presentation

A term male newborn presented with abdominal distension and bilious vomiting shortly after birth. Physical examination revealed a palpable abdominal mass. Ultrasound showed a dilated bowel loop with a blind-ending tubular structure suggestive of Meckel's diverticulum. Surgical resection identified a diverticulum 30 cm from the ileocecal valve. Histological examination confirmed ectopic pancreatic and epididymal tissue within the diverticulum.

Clinical discussion

The coexistence of ectopic pancreatic and epididymal tissue in Meckel's diverticulum is extremely rare. The embryological mechanism remains unclear, likely involving aberrant cell differentiation. Differential diagnosis in neonates with similar symptoms includes volvulus and Hirschsprung's disease. Imaging and histopathology are crucial for diagnosis. This case underscores the diverse ectopic tissue potential in Meckel's diverticulum and the importance of thorough evaluation.

Conclusion

Ectopic tissue in Meckel's diverticulum should be considered in differential diagnoses of neonatal abdominal obstruction. Awareness and timely surgical intervention are vital for management.
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新生儿伴有胰腺和附睾组织异位的梅克尔憩室
eckel憩室是一种先天性异常,约占人口的2%,是由于胎儿发育期间小肠导管未完全闭合所致。虽然通常没有症状,但它会引起阻塞和出血等并发症。憩室内的异位组织,如胃和胰腺组织,有报道。本文报告一例新生儿梅克尔憩室胰腺和附睾组织异位的病例,强调组织病理学检查的重要性。一例足月男婴出生后不久出现腹胀和胆汁性呕吐。体格检查发现腹部可触及肿块。超声显示肠袢扩张伴盲尾管状结构提示梅克尔憩室。手术切除发现离回盲瓣30厘米处有憩室。组织学检查证实憩室内胰腺和附睾组织异位。梅克尔憩室同时存在异位胰腺和附睾组织是极为罕见的。胚胎学机制尚不清楚,可能涉及异常细胞分化。有类似症状的新生儿的鉴别诊断包括肠扭转和先天性巨结肠病。影像学和组织病理学对诊断至关重要。本病例强调了Meckel憩室的多种异位组织潜能和全面评估的重要性。结论新生儿腹壁梗阻的鉴别诊断应考虑Meckel憩室异位组织。认识和及时的手术干预对治疗至关重要。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
1116
审稿时长
46 days
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