Evaluation of an updated pencil beam algorithm for enhanced dosimetric accuracy in stereotactic radiotherapy

IF 2.7 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Physica Medica-European Journal of Medical Physics Pub Date : 2025-03-01 Epub Date: 2025-02-16 DOI:10.1016/j.ejmp.2025.104941
Paul Retif , Motchy Saleh , Abdourahamane Djibo Sidikou , Romain Letellier , Anwar Al Salah , Estelle Pfletschinger , Fabian Taesch , Emilie Verrecchia-Ramos , Xavier Michel
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Abstract

Introduction

This study evaluates enhancements introduced in version 4.0 of Brainlab’s Pencil Beam algorithm within the Elements treatment planning system (TPS) for radiotherapy dose calculations. These updates include a new scatter model to improve dose calculation accuracy and updated commissioning recommendations involving asynchronous sweeping gap (a-SG) measurements to refine multileaf collimator (MLC) parameters such as dynamic leaf shift (DLS) and tongue-and-groove (TG) size.

Materials and methods

The original (version 3.0) and updated (version 4.0) implementations of the Pencil Beam algorithm were compared using a Varian TrueBeam STx accelerator with 6-MV flattening filter-free energy and high-definition MLC. Dosimetric accuracy was assessed through phantom-based point dose and volumetric measurements for clinical cases, including treatments for single and multiple brain metastases with volumetric modulated arc therapy (VMAT) and dynamic conformal arcs (DCA).

Results

The updated algorithm demonstrated superior performance compared to the original version. Point dose measurements showed a reduction in discrepancies between calculated and measured doses, with improvements of up to 2.1 % for smaller targets. Volumetric measurements revealed increased gamma pass rates, with improvements of up to 15.9 % at a 95 % dose threshold in VMAT and DCA treatments.

Conclusion

These findings highlight advancements in dose calculation accuracy, particularly for small fields and multiple targets. These improvements of the Pencil Beam algorithm, driven by the scatter model and enhanced MLC parameter commissioning, contribute to more reliable dose predictions. As findings are specific to the 6-MV FFF beam and TrueBeam STx system, further investigations are needed for other energies and linear accelerators.
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一种改进的铅笔束算法在立体定向放射治疗中提高剂量学精度的评价
本研究评估了Brainlab在Elements治疗计划系统(TPS)中用于放疗剂量计算的铅笔束算法4.0版本中引入的增强功能。这些更新包括用于提高剂量计算精度的新散射模型,以及涉及异步扫描间隙(a- sg)测量的更新调试建议,以改进多叶准直器(MLC)参数,如动态叶移(DLS)和舌槽(TG)尺寸。材料和方法使用瓦里安TrueBeam STx加速器,对铅笔束算法的原始(3.0版本)和更新(4.0版本)实现进行了比较,该加速器具有6 mv无压扁滤波器能量和高清MLC。剂量学准确性通过基于幻像的点剂量和体积测量对临床病例进行评估,包括使用体积调节电弧治疗(VMAT)和动态适形电弧(DCA)治疗单个和多个脑转移瘤。结果改进后的算法性能优于原算法。点剂量测量表明,计算剂量与测量剂量之间的差异有所减少,对于较小的目标,改善幅度可达2.1%。体积测量显示,在VMAT和DCA治疗中,在95%的剂量阈值下,伽马通过率提高了15.9%。结论这些发现突出了剂量计算精度的进步,特别是小范围和多靶点的剂量计算精度。这些铅笔束算法的改进,由散射模型和增强的MLC参数调试驱动,有助于更可靠的剂量预测。由于研究结果仅针对6 mv FFF束流和TrueBeam STx系统,因此需要对其他能量和线性加速器进行进一步的研究。
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来源期刊
CiteScore
6.80
自引率
14.70%
发文量
493
审稿时长
78 days
期刊介绍: Physica Medica, European Journal of Medical Physics, publishing with Elsevier from 2007, provides an international forum for research and reviews on the following main topics: Medical Imaging Radiation Therapy Radiation Protection Measuring Systems and Signal Processing Education and training in Medical Physics Professional issues in Medical Physics.
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