Hydrochar carbon derived from pistachio shell for simultaneous electrochemical sensing of glucose and lactate in sweat

IF 6.3 3区工程技术 Q1 ENGINEERING, CHEMICAL Journal of the Taiwan Institute of Chemical Engineers Pub Date : 2025-05-01 Epub Date: 2025-02-18 DOI:10.1016/j.jtice.2025.106008

Balaji Ramachandran , Pei-Xuan Hong , Ying-Chih Liao

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Abstract

Background

Glucose and lactate are critical biomarkers of human health. Monitoring their concentrations in sweat is essential for diagnosing of various diseases. Due to the low concentration of biomarkers in sweat, developing highly sensitive and selective sensing material is crucial for accurate detection.

Methods

Hydrochar carbon (HC) was prepared through hydrothermal carbonization using pistachio shells. Due to the carbonyl and carboxyl functional groups on the surface of HC, the HC-modified screen-printed carbon electrode (HC/SPCE) is anticipated to significantly enhance the properties associated with electrochemical sensing.

Significant findings

A biomass-derived HC is for the simultaneous electrochemical detection of glucose and lactate. The HC/SPCE exhibited excellent selectivity, reproducibility, stability, and low LOD for the detection of glucose 0.28 µM and lactate 0.37 µM were established through differential pulse voltammetry (DPV) analysis. Furthermore, HC/SPCE exhibited remarkably in real sweat sample analysis with high recovery of 99.8 %, positioning it as a highly promising sensor candidate for portable and cost-effective on-site detection of crucial sweat biomarkers.

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从开心果壳中提取的碳氢化合物，用于同时电化学感应汗液中的葡萄糖和乳酸

葡萄糖和乳酸是人类健康的重要生物标志物。监测它们在汗液中的浓度对于诊断各种疾病至关重要。由于汗液中生物标志物的浓度较低，开发高灵敏度和选择性的传感材料对于准确检测至关重要。方法以开心果壳为原料，采用水热炭化法制备碳氢化合物。由于HC表面的羰基和羧基官能团，HC修饰的丝网印刷碳电极（HC/SPCE）有望显著提高与电化学传感相关的性能。重要发现sa生物质衍生HC可用于葡萄糖和乳酸的同时电化学检测。通过差分脉冲伏安法（DPV）分析，HC/SPCE对葡萄糖0.28µM和乳酸0.37µM的检测具有良好的选择性、重复性、稳定性和低LOD。此外，HC/SPCE在真实汗液样品分析中表现出色，回收率高达99.8%，这使其成为一种非常有前途的便携式、低成本的关键汗液生物标志物现场检测传感器。

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来源期刊

Journal of the Taiwan Institute of Chemical Engineers 工程技术-工程：化工

CiteScore

9.10

自引率

14.00%

发文量

362

审稿时长

35 days

期刊介绍： Journal of the Taiwan Institute of Chemical Engineers (formerly known as Journal of the Chinese Institute of Chemical Engineers) publishes original works, from fundamental principles to practical applications, in the broad field of chemical engineering with special focus on three aspects: Chemical and Biomolecular Science and Technology, Energy and Environmental Science and Technology, and Materials Science and Technology. Authors should choose for their manuscript an appropriate aspect section and a few related classifications when submitting to the journal online.