Polymerized Salicylic Acid Microparticles Reduce the Progression and Formation of Human Neutrophil Extracellular Traps (NET)s (Adv. Healthcare Mater. 5/2025)

IF 9.6 2区 医学 Q1 ENGINEERING, BIOMEDICAL Advanced Healthcare Materials Pub Date : 2025-02-18 DOI:10.1002/adhm.202570030
Emma R. Brannon, Logan D. Piegols, Gillian Cady, Daniel Kupor, Xueqi Chu, M. Valentina Guevara, Mariana R.N. Lima, Yogendra Kanthi, David J. Pinsky, Kathryn E. Uhrich, Omolola Eniola-Adefeso
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Abstract

Neutrophil Internalization of Poly-SA Microparticle-Drug

Neutrophils are shown to internalize Poly-SA particles, a polymeric particle-based therapeutic designed to release salicylic acid inside immune cells. In article 2400443, Omolola Eniola-Adefeso and co-workers investigate alteration in NETosis, a neutrophil-specific inflammatory pathway, in response to Poly-SA particles.

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聚合水杨酸微粒减少人类中性粒细胞胞外陷阱(NET)的进展和形成(Adv. Healthcare Mater. 5/2025)
中性粒细胞内化聚sa颗粒药物中性粒细胞内化聚sa颗粒,聚sa颗粒是一种基于聚合物颗粒的治疗药物,旨在释放免疫细胞内的水杨酸。在文章2400443中,Omolola Eniola-Adefeso及其同事研究了Poly-SA颗粒对中性粒细胞特异性炎症通路NETosis的影响。
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来源期刊
Advanced Healthcare Materials
Advanced Healthcare Materials 工程技术-生物材料
CiteScore
14.40
自引率
3.00%
发文量
600
审稿时长
1.8 months
期刊介绍: Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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