Synergizing metabolomics and artificial intelligence for advancing precision oncology.

IF 13.8 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Trends in molecular medicine Pub Date : 2025-08-01 Epub Date: 2025-02-15 DOI:10.1016/j.molmed.2025.01.016
Yipeng Xu, Xiaojuan Jiang, Zeping Hu
{"title":"Synergizing metabolomics and artificial intelligence for advancing precision oncology.","authors":"Yipeng Xu, Xiaojuan Jiang, Zeping Hu","doi":"10.1016/j.molmed.2025.01.016","DOIUrl":null,"url":null,"abstract":"<p><p>Metabolomics has emerged as a transformative tool in precision oncology, with substantial potential for advancing biomarker discovery, monitoring treatment responses, and aiding drug development. Integrating artificial intelligence (AI) into metabolomics optimizes data acquisition and analysis, facilitating the interpretation of complex metabolic networks and enabling more effective multiomics integration. In this opinion, we explore recent advances in the application of metabolomics within precision oncology, emphasizing the unique advantages that AI-driven metabolomics offers. We propose that AI not only complements but also amplifies the potential of current platforms, accelerating research progress and ultimately improving patient outcomes. Finally, we discuss the opportunities and challenges involved in translating AI-driven metabolomics into clinical practice for precision oncology.</p>","PeriodicalId":23263,"journal":{"name":"Trends in molecular medicine","volume":" ","pages":"692-701"},"PeriodicalIF":13.8000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in molecular medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.molmed.2025.01.016","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/15 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Metabolomics has emerged as a transformative tool in precision oncology, with substantial potential for advancing biomarker discovery, monitoring treatment responses, and aiding drug development. Integrating artificial intelligence (AI) into metabolomics optimizes data acquisition and analysis, facilitating the interpretation of complex metabolic networks and enabling more effective multiomics integration. In this opinion, we explore recent advances in the application of metabolomics within precision oncology, emphasizing the unique advantages that AI-driven metabolomics offers. We propose that AI not only complements but also amplifies the potential of current platforms, accelerating research progress and ultimately improving patient outcomes. Finally, we discuss the opportunities and challenges involved in translating AI-driven metabolomics into clinical practice for precision oncology.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
协同代谢组学和人工智能推进精准肿瘤学。
代谢组学已经成为精确肿瘤学的一种变革性工具,在推进生物标志物发现、监测治疗反应和帮助药物开发方面具有巨大潜力。将人工智能(AI)集成到代谢组学中可以优化数据采集和分析,促进对复杂代谢网络的解释,并实现更有效的多组学集成。在这种观点下,我们探讨了代谢组学在精确肿瘤学中应用的最新进展,强调了人工智能驱动的代谢组学提供的独特优势。我们认为,人工智能不仅可以补充,还可以放大现有平台的潜力,加速研究进展,最终改善患者的治疗效果。最后,我们讨论了将人工智能驱动的代谢组学转化为精确肿瘤学临床实践所涉及的机遇和挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Trends in molecular medicine
Trends in molecular medicine 医学-生化与分子生物学
CiteScore
24.60
自引率
0.00%
发文量
142
审稿时长
6-12 weeks
期刊介绍: Trends in Molecular Medicine (TMM) aims to offer concise and contextualized perspectives on the latest research advancing biomedical science toward better diagnosis, treatment, and prevention of human diseases. It focuses on research at the intersection of basic biology and clinical research, covering new concepts in human biology and pathology with clear implications for diagnostics and therapy. TMM reviews bridge the gap between bench and bedside, discussing research from preclinical studies to patient-enrolled trials. The major themes include disease mechanisms, tools and technologies, diagnostics, and therapeutics, with a preference for articles relevant to multiple themes. TMM serves as a platform for discussion, pushing traditional boundaries and fostering collaboration between scientists and clinicians. The journal seeks to publish provocative and authoritative articles that are also accessible to a broad audience, inspiring new directions in molecular medicine to enhance human health.
期刊最新文献
Decoding atopic dermatitis: pathophysiology, clinical diagnosis, and treatments. Patient-specific trophoblast stem cells for placental medicine. Recent developments in cancer immuno-interception strategies. cAMP and mitochondrial dysfunction in cancer cachexia. Decoding GPX4 regulation in ferroptosis: mechanisms and therapeutic implications.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1