Péter Pankovics, Benigna Balázs, Ákos Boros, Gábor Nagy, Sándor Szekeres, Gábor Reuter
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引用次数: 0
Abstract
Since 2012, sakobuvirus and sakobuvirus-like (family Picornaviridae) sequences have been detected in felines, wild boars, badgers, and fur seals. In this study, we determined the genome sequence of a novel sakobuvirus identified in faecal samples from European badgers (Meles meles) in Hungary. The strain SakV/badger/B40B/2022/HUN (PQ382029) has a type IV internal ribosome entry site (IRES) and'barbell-like' structures in its 5' and 3’UTRs, with a genomic layout that matches the L-1AB-1C-1D/2AH − Box/NC-2B-2C/3A-3B-3C-3D structure. The most closely related strain, SaKoV/Badger/3A_2019/ITA (OP293080), shows 82.8%, 82.5%, and 80.4% amino acid sequence identity in the proteins P1, 2C, and 3CD, respectively, indicating that different sakobuviruses can potentially circulate among members of the same host species in geographically different regions.
期刊介绍：
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.
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