Jacqueline H Stephens, Phong Phu Nguyen, Amanda Machell, Linett Sanchez, Eng H Ooi, A Simon Carney, Trent Lewis
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引用次数: 0
Abstract
Objective: Otitis Media (OM) - ear infection - can lead to hearing loss and associated developmental delay. There are several subgroups of OM which can be difficult to diagnose accurately, even for experienced clinicians. AI and machine learning algorithms for OM diagnosis are evolving but typically only focus on one defined diagnostic feature of OM. This study aimed to establish if combining otoscopic and tympanometry data improves the diagnostic accuracy of a ML algorithm for diagnosing OM and its various subgroups.
Methods: We used an existing dataset containing data from 813 school-aged children (aged five to eight years) from 10 Aboriginal communities in remote South Australia. Data were collected between 2009 and 2011. All children underwent video otoscopy and tympanometry assessment of both ears and diagnosis of OM was made by otorhinolaryngology (ENT) surgeons. After data augmentation and preprocessing, the database contained 15,057 samples with matched video otoscopy and tympanometry data (normal: n = 8,239; abnormal: n = 6,746). Support Vector Machine models were used to build the ML system.
Results: By combining tympanometry data with the probability prediction of the single otoscopy model, the accuracy of the system increased from 78 % (otoscopy data) to 82 % (otoscopy and tympanometry data).
Conclusion: Compared to diagnosis based solely on otoscopy data, combining otoscopy and tympanometry data increased the diagnostic accuracy of the ML algorithm. This approach could be used to support the accurate diagnosis of OM in children and can facilitate timely and appropriate treatment, especially in rural and remote areas.
期刊介绍:
The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.