Pharmacist administration of long-acting injectable medications for substance use disorders: A scoping review.

Abstract

Introduction: Using long-acting injectable (LAI) medications increases treatment adherence and promotes positive outcomes for patients with substance use disorders (SUD). Despite documented benefits that LAI medications can have over their oral counterparts, they continue to be underused. With the expansion of pharmacists' scope of practice for medication administration services, there is a need to document and evaluate the benefits of pharmacist engagement in LAI administration services for SUD and identify growth opportunities. Methods: A PubMed database search for articles related to a pharmacist's role in LAI administration services for buprenorphine and naltrexone was conducted. Articles published before December 15, 2023, and in English describing or reporting outcomes of pharmacists administering LAI buprenorphine or LAI naltrexone in the United States were included. Results: A total of 56 articles were identified in the search process. After removing duplicate citations and exploring references and similar article recommendations, a total of 5 articles were included in the final analysis. All 5 articles discussed pharmacist administration of LAI naltrexone, and no articles discussed pharmacist administration of LAI buprenorphine. Outcomes for each article varied and included cost analyses, implementation procedures, and identified barriers. Discussion: Current literature on pharmacist-administered LAI services is limited. With many states allowing pharmacist administration of LAI medications, there is a significant opportunity to expand patient access to LAI medications for SUD in the pharmacy setting. Standardized training on LAI administration, development of standard operating procedures, and clarity on reimbursement policies are needed to help accelerate the implementation of pharmacist-administered LAI services.