The effect of ketamine-assisted group therapy on treatment-resistant mental health conditions in firefighters: a prospective observational case series.

Vivian Wl Tsang, Michelle Cq Lin, Cassandra M Choles, Pamela Kryskow
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Abstract

Objective: Firefighters display elevated risk for diagnoses of mental health illnesses. Psychedelic-assisted therapies show promise in the treatment of clinically challenging conditions. This observational case series analyzed data from firefighters with mental health diagnoses who participated in a 12-week ketamine-assisted group therapy treatment plan.

Methods: Questionnaire scores (GAD-7; PHQ-9; PCL-5; B-IPF) collected throughout the program were scored and statistically analyzed for changes. Qualitative data were analyzed through thematic analysis.

Results: Significant decreases with large effect sizes were detected in GAD-7 and PCL-5 scores post-completion in the 12-week treatment plan, which persisted 6 months later. Participants noted it was beneficial being in a cohort with fellow firefighters.

Conclusions: Statistically and clinically significant improvements to PTSD and anxiety diagnoses were detected in the cohort of firefighters after the RTT-KAT program, with results retained six months post treatment.

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目标:消防员被诊断患有精神疾病的风险较高。迷幻药辅助疗法在治疗具有临床挑战性的病症方面大有可为。本观察性病例系列分析了有心理健康诊断的消防员的数据,他们参加了为期 12 周的氯胺酮辅助小组治疗计划:方法:对整个治疗过程中收集的问卷分数(GAD-7;PHQ-9;PCL-5;B-IPF)进行评分,并对其变化进行统计分析。通过主题分析法对定性数据进行分析:结果:在完成为期 12 周的治疗计划后,发现 GAD-7 和 PCL-5 分数显著下降,且影响大小较大,这种情况在 6 个月后依然存在。参加者指出,与其他消防员一起参加小组活动很有益处:结论:在接受 RTT-KAT 计划治疗后,消防员队列中的创伤后应激障碍和焦虑诊断在统计和临床上都有明显改善,并且在治疗后 6 个月仍有效果。
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