Preparation and antibacterial properties of benzisothiazolinone quaternized chitosan derivatives for sustainable fuel preservation

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED Carbohydrate Polymers Pub Date : 2025-02-19 DOI:10.1016/j.carbpol.2025.123379

Lijia Liu , Mengyao Yuan , Jingli Huang , Lihua Geng , Ning Wu , Yang Yue , Jing Wang , Quanbin Zhang

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引用次数: 0

Abstract

1,2-Benzisothiazol-3(2H)-one (BIT) has strong antibacterial activity, but its water insolubility and skin toxicity effects hinder its application in the antibacterial domain of the fuel system. In this study, benzisothiazolinone quaternized chitosan derivative (HACCBIT) was synthesized by intercalated quaternized chitosan with 1,2-benzisothiazolin-3-one-based anions (BIT-COO−) via ion-exchange reactions. HACCBIT exhibits enhanced aqueous solubility and remarkable biocompatibility. It exhibited significant antibacterial and antibiofilm effects against gram-negative bacteria (Escherichia coli), gram-positive bacteria (Staphylococcus aureus) as well as microbial contaminants isolated from stored aviation fuels (Sediminibacterium salmoneum and Lysinibacillus sphaericus) by induced cytoplasmic leakage and membrane permeability. Furthermore, HACCBIT also inhibited the corrosion of the 7050‑aluminum alloy used in fuel tanks for >84 h. This study demonstrated that covalently linking BIT to chitosan via electronic splicing techniques, effectively mitigates the deficiencies of BIT while demonstrating a unique bactericidal action against bacteria in aviation fuel. It also safeguards metal components within fuel tanks, thereby enhancing the potential of polysaccharide derivatives as effective antibacterial agents in fuel systems.

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来源期刊

Carbohydrate Polymers 化学-高分子科学

CiteScore

22.40

自引率

8.00%

发文量

1286

审稿时长

47 days

期刊介绍： Carbohydrate Polymers stands as a prominent journal in the glycoscience field, dedicated to exploring and harnessing the potential of polysaccharides with applications spanning bioenergy, bioplastics, biomaterials, biorefining, chemistry, drug delivery, food, health, nanotechnology, packaging, paper, pharmaceuticals, medicine, oil recovery, textiles, tissue engineering, wood, and various aspects of glycoscience. The journal emphasizes the central role of well-characterized carbohydrate polymers, highlighting their significance as the primary focus rather than a peripheral topic. Each paper must prominently feature at least one named carbohydrate polymer, evident in both citation and title, with a commitment to innovative research that advances scientific knowledge.