Text mining of outpatient narrative notes to predict the risk of psychiatric hospitalization.

IF 6.2 1区 医学 Q1 PSYCHIATRY Translational Psychiatry Pub Date : 2025-02-20 DOI:10.1038/s41398-025-03276-9
Vedat Verter, Fan E, Daniel Frank, Angelos Georghiou
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Abstract

The primary purpose of this paper is to investigate whether text mining of the outpatient narrative notes for patients with severe and persistent mental illness (SPMI) can strengthen the predictions concerning the probability of an upcoming hospital readmission. A five-year study of all clinical notes for SPMI patients at the outpatient clinic of a tertiary hospital was conducted. The clinical notes were studied using ensemble classification i.e., entity recognition. Confounding variables pertaining to the patient's health status were extracted by text mining. A mixed effects logistic regression model was used for estimating the re-hospitalization risk during a clinic visit. The factors included frequency and continuity of outpatient visits, alterations in medication prescriptions, the usage of long-acting anti-psychotic injections (LAIs), the presence or absence of a legal compulsory treatment order (CTO) and the hospitalizations. The appearance of certain words in the outpatient clinical notes has a statistically significant impact on the risk of an upcoming hospitalization. This study also reconfirms that the risk of a re-hospitalization of an SPMI patient is reduced by the presence of a CTO and the utilization of LAIs, whereas it is increased by the patient dropping out of outpatient care. Our findings pertaining to the risk of re-hospitalization could facilitate preventive interventions for SPMI patients with higher risk.

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门诊记事记录文本挖掘预测精神科住院风险。
本文的主要目的是探讨重度持续性精神疾病(SPMI)患者门诊叙述笔记的文本挖掘是否可以加强对即将到来的再入院概率的预测。对一家三级医院门诊的SPMI患者的所有临床记录进行了为期五年的研究。临床记录研究使用集成分类,即实体识别。通过文本挖掘提取与患者健康状况相关的混杂变量。使用混合效应logistic回归模型估计门诊就诊期间的再住院风险。这些因素包括门诊就诊的频率和连续性、药物处方的改变、长效抗精神病药物注射(LAIs)的使用、是否存在法律强制治疗令(CTO)和住院情况。门诊病历中某些词语的出现对即将住院的风险有统计学显著影响。本研究还再次证实,SPMI患者再次住院的风险因CTO的存在和LAIs的使用而降低,而因患者退出门诊治疗而增加。我们的研究结果与再次住院的风险有关,可以为高风险的SPMI患者提供预防性干预措施。
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来源期刊
CiteScore
11.50
自引率
2.90%
发文量
484
审稿时长
23 weeks
期刊介绍: Psychiatry has suffered tremendously by the limited translational pipeline. Nobel laureate Julius Axelrod''s discovery in 1961 of monoamine reuptake by pre-synaptic neurons still forms the basis of contemporary antidepressant treatment. There is a grievous gap between the explosion of knowledge in neuroscience and conceptually novel treatments for our patients. Translational Psychiatry bridges this gap by fostering and highlighting the pathway from discovery to clinical applications, healthcare and global health. We view translation broadly as the full spectrum of work that marks the pathway from discovery to global health, inclusive. The steps of translation that are within the scope of Translational Psychiatry include (i) fundamental discovery, (ii) bench to bedside, (iii) bedside to clinical applications (clinical trials), (iv) translation to policy and health care guidelines, (v) assessment of health policy and usage, and (vi) global health. All areas of medical research, including — but not restricted to — molecular biology, genetics, pharmacology, imaging and epidemiology are welcome as they contribute to enhance the field of translational psychiatry.
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