Developing and testing health warnings about alcohol and risk for breast cancer: Results from a national experiment with young adult women in the United States

IF 2.7 Q2 SUBSTANCE ABUSE Alcohol (Hanover, York County, Pa.) Pub Date : 2025-02-22 DOI:10.1111/acer.70003
Zachary B. Massey, Allison B. Anbari, Na Wang, Abigail Adediran, LaRissa L. Lawrie, Priscilla Martinez, Denis McCarthy
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Abstract

Background

This study sought to identify effective health warnings about alcohol consumption and breast cancer risk among young adult female participants.

Methods

We tested a pool of health warnings in a national pilot study. We used the most effective designs from the pilot in the main experiment where young (ages 21–29) U.S. adult female participants (N = 1038) reporting past 30-day alcohol consumption were randomly assigned into 1 of 4 conditions where they viewed a health warning about (1) mortality, (2) mastectomy, (3) hair loss, or (4) control (non-health warning message). Participants were then randomly assigned to view 1 of 2 message types within each condition: text-only or pictorial. Warnings were shown apart from products. Outcomes were message reactions (attention to and cognitive elaboration of warnings, fear, hope, and perceived message effectiveness), attitudes and beliefs (perceived severity and susceptibility to alcohol harms, and perceived response and self-efficacy to prevent alcohol harms), and behavioral intentions to stop or to reduce alcohol consumption in the next month.

Results

Multivariate analysis of covariance (MANCOVA) models testing between warning conditions showed estimated marginal means (EMM) for every health warning condition were significantly higher than the control for attention (control = 5.80 vs. mortality = 6.63, mastectomy = 6.81, hair loss = 6.83, all ps < 0.05), fear (control = 2.45 vs. mortality = 4.11, mastectomy = 4.16, hair loss = 4.02, ps < 0.05), perceived message effectiveness (control = 3.44 vs. mortality = 5.75, mastectomy = 5.82, hair loss = 6.09, ps < 0.05), and perceived severity of alcohol harms (control = 5.51 vs. mortality = 6.25, mastectomy = 6.09, hair loss = 6.35, ps < 0.05). There were no significant differences between the health warnings about cancer effects for perceived message effectiveness. EMMs for intentions to reduce alcohol consumption in the next month were significantly higher in the mortality (6.44) and hair loss (6.35) conditions versus control (5.61, ps < 0.05).

Conclusion

Exposure to health warnings about alcohol consumption and breast cancer risk (vs. control) resulted in greater attention, fear, perceived message effectiveness, perceived severity of alcohol harms, and intentions to reduce alcohol consumption.

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制定和测试关于酒精和乳腺癌风险的健康警告:来自美国年轻成年女性的全国性实验的结果。
背景:本研究旨在确定年轻成年女性参与者中有关饮酒和乳腺癌风险的有效健康警告。方法:我们在一项国家试点研究中测试了一系列健康警告。我们在主要实验中使用了最有效的设计,其中年轻(21-29岁)的美国成年女性参与者(N = 1038)报告了过去30天的酒精消费,他们被随机分配到四种情况中的一种,在四种情况下,他们看到了关于(1)死亡率、(2)乳房切除术、(3)脱发或(4)控制(非健康警告信息)的健康警告。然后,参与者被随机分配在每个条件下查看两种信息类型中的一种:纯文本或图片。除了产品外,还显示了警告信息。结果包括信息反应(对警告、恐惧、希望和感知到的信息有效性的关注和认知阐述)、态度和信念(感知到的酒精危害的严重程度和易感性、感知到的反应和预防酒精危害的自我效能),以及在下个月停止或减少饮酒的行为意图。结果:多变量协方差分析(MANCOVA)模型在警告条件之间的检验显示,每个健康警告条件的估计边际均值(EMM)显著高于注意的对照组(对照组= 5.80,死亡率= 6.63,乳房切除术= 6.81,脱发= 6.83,所有ps)。接触有关饮酒和乳腺癌风险的健康警告(与对照组相比)导致了更多的关注、恐惧、感知到的信息有效性、感知到的酒精危害的严重程度,以及减少饮酒的意图。
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