Huaiyin Liang, Yanrui Ma, Yan Zhao, Nageena Qayyum, Fatao He, Jiewei Tian, Xiyun Sun, Bin Li, Yuehua Wang, Maoyu Wu, Guangpeng Liu
{"title":"A Review on the Extraction, Structural Analysis, and Antitumor Mechanisms of <i>Sanghuangporus</i> Polysaccharides.","authors":"Huaiyin Liang, Yanrui Ma, Yan Zhao, Nageena Qayyum, Fatao He, Jiewei Tian, Xiyun Sun, Bin Li, Yuehua Wang, Maoyu Wu, Guangpeng Liu","doi":"10.3390/foods14040707","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, the bioactive compounds extracted from <i>Sanghuangporus</i>, especially polysaccharides, phenols, and triterpenoids, have attracted great interest from people due to their extensive biological activity. Among them, polysaccharides are mainly extracted from the seed bodies, mycelium, and fermentation broth of <i>Sanghuangyuan</i>, exhibiting notable effects including immunomodulation, antitumor properties, and hypoglycemic effects. This article provides a comprehensive review of the extraction process, structural characteristics, and antitumor mechanism of <i>Sanghuangyuan</i> polysaccharides. First, the different extraction methods, such as hot water extraction, enzyme-assisted extraction, and ultrasonic-assisted extraction, are summarized. Then, the structure of the <i>Sanghuangporus</i> polysaccharide is studied in detail. Moreover, the antitumor mechanisms demonstrate significant inhibitory impacts on various malignant tumors, spanning gastric, hepatic, colorectal, breast, and prostate cancers. This groundbreaking revelation is of great significance for both the food and pharmaceutical sectors, presenting innovative pathways for <i>Sanghuangyuan</i> utilization and potentially inducing advancements in product development, treatment modalities, and therapeutic interventions.</p>","PeriodicalId":12386,"journal":{"name":"Foods","volume":"14 4","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11854207/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Foods","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3390/foods14040707","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, the bioactive compounds extracted from Sanghuangporus, especially polysaccharides, phenols, and triterpenoids, have attracted great interest from people due to their extensive biological activity. Among them, polysaccharides are mainly extracted from the seed bodies, mycelium, and fermentation broth of Sanghuangyuan, exhibiting notable effects including immunomodulation, antitumor properties, and hypoglycemic effects. This article provides a comprehensive review of the extraction process, structural characteristics, and antitumor mechanism of Sanghuangyuan polysaccharides. First, the different extraction methods, such as hot water extraction, enzyme-assisted extraction, and ultrasonic-assisted extraction, are summarized. Then, the structure of the Sanghuangporus polysaccharide is studied in detail. Moreover, the antitumor mechanisms demonstrate significant inhibitory impacts on various malignant tumors, spanning gastric, hepatic, colorectal, breast, and prostate cancers. This groundbreaking revelation is of great significance for both the food and pharmaceutical sectors, presenting innovative pathways for Sanghuangyuan utilization and potentially inducing advancements in product development, treatment modalities, and therapeutic interventions.
期刊介绍：
Foods (ISSN 2304-8158) is an international, peer-reviewed scientific open access journal which provides an advanced forum for studies related to all aspects of food research. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists, researchers, and other food professionals to publish their experimental and theoretical results in as much detail as possible or share their knowledge with as much readers unlimitedly as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, unique features of this journal:
manuscripts regarding research proposals and research ideas will be particularly welcomed
electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material
we also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
