Scutellaria baicalensis stem and leaf combat chicken-derived respiratory bacterial infection

IF 3.5 3区 医学 Q3 IMMUNOLOGY Microbial pathogenesis Pub Date : 2025-05-01 Epub Date: 2025-02-27 DOI:10.1016/j.micpath.2025.107439
Xilin Wang , Shihai Wu , Ning Guo , Feike Yu , Xiaofeng Xu , Xinghai Wang , Xiaohan Yu , Xiaoye Liu , Hong Dong
{"title":"Scutellaria baicalensis stem and leaf combat chicken-derived respiratory bacterial infection","authors":"Xilin Wang ,&nbsp;Shihai Wu ,&nbsp;Ning Guo ,&nbsp;Feike Yu ,&nbsp;Xiaofeng Xu ,&nbsp;Xinghai Wang ,&nbsp;Xiaohan Yu ,&nbsp;Xiaoye Liu ,&nbsp;Hong Dong","doi":"10.1016/j.micpath.2025.107439","DOIUrl":null,"url":null,"abstract":"<div><div>The Chinese poultry industry has witnessed rapid development, with laying hens playing a pivotal role. However, the escalating demand has led to an exponential increase in the population of laying hens raised, resulting in emerging challenges. Particularly during bacterial infections, substantial losses can be incurred. Presently, most farms heavily rely on antibiotics for disease prevention and control. Although this approach has yielded positive outcomes, prolonged usage may lead to the emergence of drug-resistant strains and residues. Consequently, research on alternative drugs has been initiated due to antibiotic prohibition and growing pathogen resistance. Chinese herbal medicine holds significant prominence across various domains, including animal husbandry and disease treatment, owing to its traditional roots in China. <em>Scutellaria baicalensis</em> is a traditional Chinese medicine derived from the dried root of the labiatae family plant <em>Scutellaria baicalensis</em> that possesses bitter taste and cold properties while exhibiting effects such as heat clearance, dampness elimination, lung purification, fire expulsion and heat detoxification. The aboveground components of <em>Scutellaria baicalensis</em> encompass stems and leaves, which yield approximately three times more than their root counterparts as traditional Chinese medicine resources. <em>Sculltllarla bactlalensls</em> products have been successfully applied in animal husbandry with therapeutic effects against sore throat, respiratory diseases, and heat detoxification. Therefore, in pursuit of economic sustainability, this study aims at developing an extract from <em>Scutellaria baicalensis</em> stems and leaves for treating respiratory bacterial infections among laying hens. The findings indicate that this extract exhibits excellent therapeutic efficacy against respiratory diseases among laying hens by reducing inflammatory cell levels within their lungs.</div></div>","PeriodicalId":18599,"journal":{"name":"Microbial pathogenesis","volume":"202 ","pages":"Article 107439"},"PeriodicalIF":3.5000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbial pathogenesis","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0882401025001640","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/27 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

The Chinese poultry industry has witnessed rapid development, with laying hens playing a pivotal role. However, the escalating demand has led to an exponential increase in the population of laying hens raised, resulting in emerging challenges. Particularly during bacterial infections, substantial losses can be incurred. Presently, most farms heavily rely on antibiotics for disease prevention and control. Although this approach has yielded positive outcomes, prolonged usage may lead to the emergence of drug-resistant strains and residues. Consequently, research on alternative drugs has been initiated due to antibiotic prohibition and growing pathogen resistance. Chinese herbal medicine holds significant prominence across various domains, including animal husbandry and disease treatment, owing to its traditional roots in China. Scutellaria baicalensis is a traditional Chinese medicine derived from the dried root of the labiatae family plant Scutellaria baicalensis that possesses bitter taste and cold properties while exhibiting effects such as heat clearance, dampness elimination, lung purification, fire expulsion and heat detoxification. The aboveground components of Scutellaria baicalensis encompass stems and leaves, which yield approximately three times more than their root counterparts as traditional Chinese medicine resources. Sculltllarla bactlalensls products have been successfully applied in animal husbandry with therapeutic effects against sore throat, respiratory diseases, and heat detoxification. Therefore, in pursuit of economic sustainability, this study aims at developing an extract from Scutellaria baicalensis stems and leaves for treating respiratory bacterial infections among laying hens. The findings indicate that this extract exhibits excellent therapeutic efficacy against respiratory diseases among laying hens by reducing inflammatory cell levels within their lungs.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
黄芩茎叶对抗鸡源性呼吸道细菌感染
中国家禽业发展迅速,其中蛋鸡起着举足轻重的作用。然而,不断增长的需求导致蛋鸡数量呈指数级增长,从而带来了新的挑战。特别是在细菌感染期间,可能会造成重大损失。目前,大多数农场严重依赖抗生素来预防和控制疾病。虽然这种方法已经产生了积极的结果,但长期使用可能导致耐药菌株和残留物的出现。因此,由于抗生素的禁止和日益增长的病原体耐药性,替代药物的研究已经开始。中草药由于其在中国的传统根源,在包括畜牧业和疾病治疗在内的各个领域都占有重要地位。黄芩(Scutellaria baicalensis)是由唇科植物黄芩(Scutellaria baicalensis)的干燥根提取而成的中药,具有苦味和寒性,同时具有清热、祛湿、清肺、排火、解热等功效。黄芩的地上成分包括茎和叶,其产量约为其根的三倍。乳杆菌产品已成功应用于畜牧业,具有治疗咽喉痛、呼吸系统疾病、解热解毒等功效。因此,为了追求经济的可持续性,本研究旨在开发黄芩茎叶提取物,用于治疗蛋鸡呼吸道细菌感染。研究结果表明,该提取物通过降低蛋鸡肺部炎症细胞水平,对蛋鸡呼吸系统疾病具有良好的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Microbial pathogenesis
Microbial pathogenesis 医学-免疫学
CiteScore
7.40
自引率
2.60%
发文量
472
审稿时长
56 days
期刊介绍: Microbial Pathogenesis publishes original contributions and reviews about the molecular and cellular mechanisms of infectious diseases. It covers microbiology, host-pathogen interaction and immunology related to infectious agents, including bacteria, fungi, viruses and protozoa. It also accepts papers in the field of clinical microbiology, with the exception of case reports. Research Areas Include: -Pathogenesis -Virulence factors -Host susceptibility or resistance -Immune mechanisms -Identification, cloning and sequencing of relevant genes -Genetic studies -Viruses, prokaryotic organisms and protozoa -Microbiota -Systems biology related to infectious diseases -Targets for vaccine design (pre-clinical studies)
期刊最新文献
Genomic characterization, antimicrobial resistance and virulence profiles of Klebsiella pneumoniae isolated from mink in Northern China Identifying mitochondria-related signatures for tuberculosis diagnosis through machine learning on single-cell transcriptomics data and experimental verification The gut microbiome as a modulator of antibiotic resistance: Mechanisms, dynamics, and therapeutic interventions Bifidobacterium longum subsp. infantis B8762 modulates the infant gut-lung axis via microbial and metabolic reprogramming The ESX-3 secretion system in mycobacteria: Evolution, structure, and multifunctional roles in pathogenesis
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1