{"title":"Long-term results of late open conversions with partial or total removal of noninfected stent grafts after failed endovascular aneurysm repair","authors":"Tuukka Kaartama MD , Davide Esposito MD , Maria Giulia Pascucci MD , Sergio Zacá MD , Domenico Angiletta PhD , Efrem Civilini PhD , Maarit Venermo PhD , Giovanni Pratesi PhD , Pekka Aho PhD","doi":"10.1016/j.jvs.2025.02.023","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Open surgical conversion after failed EVAR has become more common. Our aim was to compare the short- and long-term results of late open conversions for noninfectious indications with partial or total stent graft removal.</div></div><div><h3>Methods</h3><div>Our study is a retrospective, multicenter observational study of late open conversions performed in five hospitals between January 1997 and June 2024. Patients who underwent a partial or total removal of a stent graft more than 30 days after EVAR for noninfectious indications were included in the analysis and divided into two groups: partial conversion (PC) and total conversion (TC). The primary outcomes were 30-day mortality, 5-year survival, and freedom from late complications. The secondary outcomes were perioperative cardiovascular complications, length of hospital stay, and 5-year freedom from reinterventions and from aneurysm-related death.</div></div><div><h3>Results</h3><div>The analysis included 97 patients: 57 (58.8%) in the PC group and 40 (41.2%) in the TC group. The 30-day mortality in the PC group was lower compared with the TC group (14.3% vs 24.3%; odds ratio, 0.52; <em>P</em> = .220), although the difference did not reach statistical significance. The estimated 5-year overall survival was similar in the PC and TC groups (58.8% vs 59.8%; <em>P</em> = .726). The patients in the PC group had no infections or thrombosis and a similar freedom from late complications compared with the TC group (81.2% vs 84.0%; <em>P</em> = .788). A subgroup analysis comparing the preoperative CTA scans and intraoperative observations revealed an occult endoleak in 22 patients (22.7%), and in the 12 patients (12.4%) who underwent surgery for a suspected endoleak, none were identified during the procedure.</div></div><div><h3>Conclusions</h3><div>PC seems to be noninferior to TC and possibly even safer, with a trend toward lower mortality in the short term. No differences in mortality or complications were found between the groups during long-term follow-up.</div></div>","PeriodicalId":17475,"journal":{"name":"Journal of Vascular Surgery","volume":"81 6","pages":"Pages 1335-1342"},"PeriodicalIF":3.6000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0741521425003489","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
Open surgical conversion after failed EVAR has become more common. Our aim was to compare the short- and long-term results of late open conversions for noninfectious indications with partial or total stent graft removal.
Methods
Our study is a retrospective, multicenter observational study of late open conversions performed in five hospitals between January 1997 and June 2024. Patients who underwent a partial or total removal of a stent graft more than 30 days after EVAR for noninfectious indications were included in the analysis and divided into two groups: partial conversion (PC) and total conversion (TC). The primary outcomes were 30-day mortality, 5-year survival, and freedom from late complications. The secondary outcomes were perioperative cardiovascular complications, length of hospital stay, and 5-year freedom from reinterventions and from aneurysm-related death.
Results
The analysis included 97 patients: 57 (58.8%) in the PC group and 40 (41.2%) in the TC group. The 30-day mortality in the PC group was lower compared with the TC group (14.3% vs 24.3%; odds ratio, 0.52; P = .220), although the difference did not reach statistical significance. The estimated 5-year overall survival was similar in the PC and TC groups (58.8% vs 59.8%; P = .726). The patients in the PC group had no infections or thrombosis and a similar freedom from late complications compared with the TC group (81.2% vs 84.0%; P = .788). A subgroup analysis comparing the preoperative CTA scans and intraoperative observations revealed an occult endoleak in 22 patients (22.7%), and in the 12 patients (12.4%) who underwent surgery for a suspected endoleak, none were identified during the procedure.
Conclusions
PC seems to be noninferior to TC and possibly even safer, with a trend toward lower mortality in the short term. No differences in mortality or complications were found between the groups during long-term follow-up.
目的:EVAR失败后的开放性手术转归越来越普遍。我们的目的是比较非感染性指征的晚期开放性手术与部分或全部支架移除的短期和长期结果。方法:我们的研究是一项回顾性、多中心观察性研究,对1997年1月至2024年6月期间在五家医院进行的晚期开放转换进行研究。在非感染性指征EVAR后超过30天接受部分或全部支架移除的患者被纳入分析,并分为两组:部分(PC)和完全转换(TC)。主要结局为30天死亡率、5年生存率和无晚期并发症。次要结局是围手术期心血管并发症、住院时间和5年无再干预和动脉瘤相关死亡。结果:共纳入97例患者,其中PC组57例(58.8%),TC组40例(41.2%)。PC组30天死亡率低于TC组(14.3% vs 24.3%, OR = 0.52, p = 0.220),但差异无统计学意义。估计PC组和TC组的5年总生存率相似(58.8% vs 59.8%, p = .726)。与TC组相比,PC组患者无感染或血栓形成,晚期并发症的发生率相似(81.2% vs 84%, p = .788)。一项比较术前CTA扫描和术中观察的亚组分析显示,22例(22.7%)患者存在隐匿性内漏,而在12例(12.4%)因疑似内漏而接受手术的患者中,在手术过程中没有发现任何内漏。结论:部分转换似乎不逊色于完全转换,甚至可能更安全,在短期内有降低死亡率的趋势。在长期随访中,两组之间的死亡率和并发症没有差异。
期刊介绍:
Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.