Enhancing atrial fibrillation detection in PPG analysis with sparse labels through contrastive learning

IF 4.8 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computer methods and programs in biomedicine Pub Date : 2025-02-27 DOI:10.1016/j.cmpb.2025.108698
Hong Wu , Qihan Hu , Daomiao Wang , Shiwei Zhu , Cuiwei Yang
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Abstract

Background

With the advancements in wearable technology, photoplethysmography (PPG) has emerged as a promising technique for detecting atrial fibrillation (AF) due to its ability to capture cardiovascular information. However, current deep learning-based methods has strict requirements on the quantity of labeled data. To overcome this limitation, we explore the performance of self-supervised contrastive learning in PPG-based AF detection.

Methods

Our method initially utilizes 1,209 h of unlabeled PPG data from the VitalDB database, conducting self-supervised pretraining using two contrastive learning frameworks, SimCLR and BYOL. Subsequently, the weights of the encoder are transferred and fine-tuned on a small amount of labeled PPG data to complete the AF detection task, including the selected MIMIC III, UMass, and DeepBeat datasets. In the realm of contrastive learning, we investigated seven data augmentation operations to explore their composite and preferred combinations, as well as the effects of double-sided and single-sided transformations.

Results

Our research ultimately demonstrated that the preferred combination, incorporating single-sided transformation with the Drift operation, is most suitable for PPG data. Notably, even with only 1 %, 20 %, and 1 % of the training data from the three datasets used for fine-tuning, our approach achieves better F1 scores compared to supervised learning on the respective complete training sets. Additionally, on the 0.01 % DeepBeat training set, fine-tuning still showed a clear advantage over supervised learning.

Conclusion

Appropriate self-supervised contrastive pretraining effectively leverages a substantial amount of existing unlabeled PPG data, thus reducing the reliance on labeled data for AF detection, and offering a possible solution to address the limitations posed by the scarcity of labels.
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通过对比学习增强稀疏标记在PPG分析中的房颤检测
随着可穿戴技术的进步,光电容积脉搏波(PPG)由于其捕获心血管信息的能力而成为一种很有前途的检测心房颤动(AF)的技术。然而,目前基于深度学习的方法对标注数据的数量有严格的要求。为了克服这一限制,我们探索了基于ppg的AF检测中自监督对比学习的性能。方法首先利用VitalDB数据库中1209 h的未标记PPG数据,使用SimCLR和BYOL两种对比学习框架进行自监督预训练。随后,编码器的权重被转移并在少量标记的PPG数据上进行微调,以完成自动对焦检测任务,包括所选的MIMIC III、UMass和DeepBeat数据集。在对比学习领域,我们研究了七种数据增强操作,以探索它们的复合和首选组合,以及双面和单面转换的效果。结果我们的研究最终表明,将单面变换与漂移操作相结合的首选组合最适合PPG数据。值得注意的是,即使只使用三个数据集中的1%、20%和1%的训练数据进行微调,与在各自完整的训练集上的监督学习相比,我们的方法也获得了更好的F1分数。此外,在0.01%的DeepBeat训练集上,微调仍然比监督学习显示出明显的优势。结论适当的自我监督对比预训练有效地利用了大量现有的未标记PPG数据,从而减少了AF检测对标记数据的依赖,并为解决标签稀缺所带来的限制提供了一种可能的解决方案。
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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