Developing a Strategy for Prevention of Avoidable Postcolonoscopy Colorectal Cancers: Current and Future Perspectives

IF 25.7 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Gastroenterology Pub Date : 2025-03-11 DOI:10.1053/j.gastro.2024.12.003

Nanette S. Van roermund, Joep E.G. Ijspeert, Evelien Dekker

{"title":"Developing a Strategy for Prevention of Avoidable Postcolonoscopy Colorectal Cancers: Current and Future Perspectives","authors":"Nanette S. Van roermund, Joep E.G. Ijspeert, Evelien Dekker","doi":"10.1053/j.gastro.2024.12.003","DOIUrl":null,"url":null,"abstract":"Colonoscopy with removal of adenomas and serrated polyps significantly decreases the risk of colorectal cancer (CRC). However, a significant number of CRCs diagnosed with the use of colonoscopy are found in individuals that underwent a colonoscopy in the years preceding the diagnosis.1 These so-called postcolonoscopy colorectal cancers (PCCRCs) expose the limitations of colonoscopy in preventing CRC. A small percentage of PCCRCs seem to be unavoidable because they are caused by biological factors such as accelerated cancer development.2 However, the majority of PCCRCs are likely caused by a polyp being missed or incompletely resected during colonoscopy.2,3 Therefore, awareness and improvement of the quality of colonoscopy plays a pivotal role in the prevention of avoidable PCCRCs. In this commentary, we highlight the current understanding of the terminology, incidence, and causes of PCCRCs. Then we discuss potential strategies to prevent avoidable PCCRCs in the future.","PeriodicalId":12590,"journal":{"name":"Gastroenterology","volume":"56 1","pages":""},"PeriodicalIF":25.7000,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1053/j.gastro.2024.12.003","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Colonoscopy with removal of adenomas and serrated polyps significantly decreases the risk of colorectal cancer (CRC). However, a significant number of CRCs diagnosed with the use of colonoscopy are found in individuals that underwent a colonoscopy in the years preceding the diagnosis.¹ These so-called postcolonoscopy colorectal cancers (PCCRCs) expose the limitations of colonoscopy in preventing CRC. A small percentage of PCCRCs seem to be unavoidable because they are caused by biological factors such as accelerated cancer development.² However, the majority of PCCRCs are likely caused by a polyp being missed or incompletely resected during colonoscopy.²^,³ Therefore, awareness and improvement of the quality of colonoscopy plays a pivotal role in the prevention of avoidable PCCRCs. In this commentary, we highlight the current understanding of the terminology, incidence, and causes of PCCRCs. Then we discuss potential strategies to prevent avoidable PCCRCs in the future.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Gastroenterology 医学-胃肠肝病学

CiteScore

45.60

自引率

2.40%

发文量

4366

审稿时长

26 days

期刊介绍： Gastroenterology is the most prominent journal in the field of gastrointestinal disease. It is the flagship journal of the American Gastroenterological Association and delivers authoritative coverage of clinical, translational, and basic studies of all aspects of the digestive system, including the liver and pancreas, as well as nutrition. Some regular features of Gastroenterology include original research studies by leading authorities, comprehensive reviews and perspectives on important topics in adult and pediatric gastroenterology and hepatology. The journal also includes features such as editorials, correspondence, and commentaries, as well as special sections like "Mentoring, Education and Training Corner," "Diversity, Equity and Inclusion in GI," "Gastro Digest," "Gastro Curbside Consult," and "Gastro Grand Rounds." Gastroenterology also provides digital media materials such as videos and "GI Rapid Reel" animations. It is abstracted and indexed in various databases including Scopus, Biological Abstracts, Current Contents, Embase, Nutrition Abstracts, Chemical Abstracts, Current Awareness in Biological Sciences, PubMed/Medline, and the Science Citation Index.