Outcomes of Older Adults With Delirium Discharged From the Emergency Department

IF 5 1区 医学 Q1 EMERGENCY MEDICINE Annals of emergency medicine Pub Date : 2025-11-01 Epub Date: 2025-03-12 DOI:10.1016/j.annemergmed.2025.02.003
Annelise S. Howick BA , Piayeng Thao BS , Kayla P. Carpenter BS , Madeline A. Boie BSc , Ian Ward A. Maia MD, PhD , Aidan F. Mullan MA , Susan M. Bower MSN, RN , Allyson K. Palmer MD, PhD , Christopher R. Carpenter MD, MSc , Shan W. Liu MD, SD , Molly M. Jeffery PhD, MPP , Fernanda Bellolio MD, MSc
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Abstract

Study objective

To compare 30-day mortality and return emergency department (ED) visits among older adults with delirium who are discharged home with those discharged home without delirium and those who are admitted to the hospital with and without delirium.

Methods

Adults aged 75 and older years were assessed for delirium using the Delirium Triage Screen followed by the Brief Confusion Assessment Method. We evaluated outcomes including return visits and 30-day mortality. Models were adjusted by age, sex, dementia, Modified Early Warning Score, and ED length of stay and summarized with adjusted relative risk (aRR) and 95% confidence intervals (CIs).

Results

The study included 22,940 visits. Among them, 202 (0.9%) delirium-positive patients were discharged, and 730 (3.2%) were admitted to the hospital to non-ICU and nonmonitored beds. Discharged patients with delirium had higher 30-day mortality (aRR 2.86, 95% CI 2.04 to 4.00) and were more likely to return to the ED within 30 days (aRR 1.52, 95% CI 1.43 to 1.61) compared with those discharged without delirium. Discharged delirium-positive patients were more likely to return to the ED within 30 days than hospitalized delirium-positive patients (aRR 1.92, 95% CI 1.41 to 1.92), though they experienced lower 30-day mortality (aRR 0.67, 95% CI 0.47 to 0.93). Age, sex, Modified Early Warning Score, dementia, and length of stay were not associated with mortality or ED return.

Conclusion

Patients discharged with delirium experienced a 3-fold increase in mortality within 30 days compared with those discharged without delirium. These findings suggest a need for more precise discharge criteria and enhanced follow-up care for delirious patients to improve safety. Implementing structured screening and tailored postdischarge support could reduce adverse outcomes in this population.
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急诊科出院的老年谵妄患者的预后
研究目的:比较出院的老年谵妄患者与无谵妄患者以及住院的谵妄患者和无谵妄患者的30天死亡率和急诊回访率。方法:对75岁及以上的成年人进行谵妄分诊筛查,随后采用简要混淆评估法。我们评估的结果包括复诊和30天死亡率。模型根据年龄、性别、痴呆、修正早期预警评分和ED住院时间进行调整,并用调整后的相对危险度(aRR)和95%置信区间(ci)进行总结。结果:该研究包括22940次访问。其中谵妄阳性202例(0.9%)出院,730例(3.2%)入住非icu及无监护床位。出院的谵妄患者30天死亡率更高(aRR 2.86, 95% CI 2.04 - 4.00),与没有谵妄的出院患者相比,更有可能在30天内返回急诊室(aRR 1.52, 95% CI 1.43 - 1.61)。出院的谵妄阳性患者比住院的谵妄阳性患者更有可能在30天内返回急诊室(aRR 1.92, 95% CI 1.41至1.92),尽管他们的30天死亡率较低(aRR 0.67, 95% CI 0.47至0.93)。年龄、性别、修正早期预警评分、痴呆和住院时间与死亡率或ED复发无关。结论:谵妄患者出院后30天内的死亡率是无谵妄患者的3倍。这些发现提示需要更精确的出院标准和加强谵妄患者的随访护理,以提高安全性。实施结构化筛查和量身定制的出院后支持可以减少这一人群的不良后果。
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来源期刊
Annals of emergency medicine
Annals of emergency medicine 医学-急救医学
CiteScore
8.30
自引率
4.80%
发文量
819
审稿时长
20 days
期刊介绍: Annals of Emergency Medicine, the official journal of the American College of Emergency Physicians, is an international, peer-reviewed journal dedicated to improving the quality of care by publishing the highest quality science for emergency medicine and related medical specialties. Annals publishes original research, clinical reports, opinion, and educational information related to the practice, teaching, and research of emergency medicine. In addition to general emergency medicine topics, Annals regularly publishes articles on out-of-hospital emergency medical services, pediatric emergency medicine, injury and disease prevention, health policy and ethics, disaster management, toxicology, and related topics.
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