Lecanemab for mild Alzheimer disease - is there a way forward?

Q2 Pharmacology, Toxicology and Pharmaceutics Drugs in Context Pub Date : 2025-03-03 eCollection Date: 2025-01-01 DOI:10.7573/dic.2024-12-2
Rajesh R Tampi
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Abstract

This Editorial reviews data on the efficacy and adverse effects of lecanemab amongst individuals with mild Alzheimer disease. Additionally, the recent controversy regarding the rejection by the EMA of a marketing authorization request for lecanemab, followed by its subsequent approval, is also discussed. The need for thoughtful discussions regarding the risks and benefits of this medication as well as the importance of developing Appropriate Use Recommendations and/or national guidelines for the use of lecanemab are also highlighted.

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本社论回顾了有关莱卡奈单抗在轻度阿尔茨海默病患者中的疗效和不良反应的数据。此外,社论还讨论了最近有关欧洲医学管理局(EMA)拒绝莱卡尼单抗上市许可申请并随后批准该药的争议。此外,还强调了就该药物的风险和益处进行深思熟虑的必要性,以及为莱卡尼单抗的使用制定适当使用建议和/或国家指南的重要性。
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来源期刊
Drugs in Context
Drugs in Context Medicine-Medicine (all)
CiteScore
5.90
自引率
0.00%
发文量
63
审稿时长
9 weeks
期刊介绍: Covers all phases of original research: laboratory, animal and human/clinical studies, health economics and outcomes research, and postmarketing studies. Original research that shows positive or negative results are welcomed. Invited review articles may cover single-drug reviews, drug class reviews, latest advances in drug therapy, therapeutic-area reviews, place-in-therapy reviews, new pathways and classes of drugs. In addition, systematic reviews and meta-analyses are welcomed and may be published as original research if performed per accepted guidelines. Editorials of key topics and issues in drugs and therapeutics are welcomed. The Editor-in-Chief will also consider manuscripts of interest in areas such as technologies that support diagnosis, assessment and treatment. EQUATOR Network reporting guidelines should be followed for each article type. GPP3 Guidelines should be followed for any industry-sponsored manuscripts. Other Editorial sections may include Editorial, Case Report, Conference Report, Letter-to-the-Editor, Educational Section.
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