Are health education effective to improve herpes zoster vaccine willingness in vulnerable elderly

IF 4.5 3区 医学 Q2 IMMUNOLOGY Vaccine Pub Date : 2025-04-30 Epub Date: 2025-03-15 DOI:10.1016/j.vaccine.2025.126975
Xiyu Zhang , Tianshuo Zhao , Xianming Cai , Wanxue Zhang , Ninghua Huang , Juan Du , Jing Zeng , Qing-bin Lu , Yuanshan Zhang , Fuqiang Cui
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Abstract

Background

Compared to other vaccines recommended for the elderly, the effectiveness of health education in improving the willingness to vaccinate the herpes zoster vaccine (HZV) in low-come residents remains unclear.

Methods

We recruited elderly participants from villages in Lingcheng District, and assigned each village to one of three health education interventions: oral health education, brochure-based health education, or video health education. The follow-up surveys were conducted immediately after each intervention. Baseline survey and the fifth follow-up were conducted at the beginning and end of the study, respectively. We assessed respondents' willingness to vaccinate the HZV under different pricing scenarios, as well as their reasons for accepting or refusing to vaccinate HVZ. Latent class growth analysis was used to identify potential similar trends in vaccination willingness.

Results

Of 1027 recruited, 946 completed 5 follow-ups. Data shows only when HZV was free, willingness to vaccinate could increase significantly across all interventions. Heterogeneity among population clusters has been identified on intervention effectiveness and comorbidity may be an important cause. Vaccine effectiveness and personal infection risk motivated acceptance, while accessibility and affordability were barriers.

Conclusion

Health education improves HZV vaccination willingness, under free pricing scenario. Lowering HZV costs through health insurance or affordable options is necessary for successful education initiatives.
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健康教育对提高老年人易感人群带状疱疹疫苗接种意愿有效吗
背景与其他推荐给老年人的疫苗相比,健康教育在提高低收入居民接种带状疱疹疫苗(HZV)意愿方面的有效性尚不清楚。方法从灵城区的村庄中招募老年人,并将每个村庄分配到三种健康教育干预措施中的一种:口腔健康教育、手册健康教育和视频健康教育。每次干预后立即进行随访调查。基线调查和第五次随访分别在研究开始和结束时进行。我们评估了受访者在不同价格情景下接种HZV的意愿,以及他们接受或拒绝接种HVZ的原因。潜在类别增长分析用于确定疫苗接种意愿的潜在相似趋势。结果入选1027例,946例完成5次随访。数据显示,只有在没有HZV的情况下,接种疫苗的意愿才能在所有干预措施中显著增加。不同人群在干预效果上存在异质性,合并症可能是重要原因。疫苗有效性和个人感染风险促使人们接受疫苗,而可及性和可负担性是障碍。结论在免费定价的情况下,健康教育提高了HZV疫苗接种意愿。通过健康保险或负担得起的选择来降低HZV成本是成功教育举措的必要条件。
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来源期刊
Vaccine
Vaccine 医学-免疫学
CiteScore
8.70
自引率
5.50%
发文量
992
审稿时长
131 days
期刊介绍: Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.
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