Regular-fat and low-fat dairy foods and cardiovascular diseases: Perspectives for future dietary recommendations.

IF 6.5 1区 医学 Q1 NUTRITION & DIETETICS American Journal of Clinical Nutrition Pub Date : 2025-03-13 DOI:10.1016/j.ajcnut.2025.03.009
Benoît Lamarche, Arne Astrup, Robert H Eckel, Emma Feeney, Ian Givens, Ronald M Krauss, Philippe Legrand, Renata Micha, Marie-Caroline Michalski, Sabita Soedamah-Muthu, Qi Sun, Frans J Kok
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Abstract

Most current dietary guidelines for the prevention of cardiovascular diseases (CVD) recommend the consumption of low-fat dairy in place of regular-fat dairy foods, one of the main sources of dietary saturated fatty acids (SFAs). Here, we summarise the data presented and discussions held - relating to the validity of such recommendations - between a panel of international nutrition research experts at a high-level closed workshop on 'Saturated Fat in Dairy and Cardiovascular Diseases', which took place in Amsterdam on 15-16 April 2024. The most recent evidence indicates that overall, consumption of milk, yogurt and cheese, irrespective of fat content, is neutrally associated with CVD risk. There is also no evidence yet from randomized controlled trials that consumption of regular-fat milk, yogurt and cheese has different effects on a broad array of cardiometabolic risk factors when compared to consumption of low-fat milk, yogurt and cheese. Thus, the body of evidence does not support differentiation between regular-fat and low-fat dairy foods in dietary guidelines for both adults and children. Strategies focusing primarily on reduction of energy-dense, nutrient-poor foods, the main source of SFAs in Western diets, rather than on the fat content of dairy foods, are more likely to benefit the population's cardiovascular health. Future research is needed to understand better the place of regular-fat and low-fat dairy foods within healthy eating patterns.

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目前,大多数预防心血管疾病(CVD)的膳食指南都建议食用低脂乳制品来替代普通脂肪乳制品食品,而普通脂肪乳制品食品是膳食中饱和脂肪酸(SFA)的主要来源之一。在此,我们总结了2024年4月15-16日在阿姆斯特丹举行的 "乳制品中的饱和脂肪与心血管疾病 "高级别闭门研讨会上,国际营养研究专家小组就此类建议的有效性所提供的数据和进行的讨论。最新的证据表明,总体而言,无论脂肪含量如何,牛奶、酸奶和奶酪的消费与心血管疾病风险的关系不大。随机对照试验也没有证据表明,与饮用低脂牛奶、酸奶和奶酪相比,饮用常脂牛奶、酸奶和奶酪对各种心脏代谢风险因素有不同的影响。因此,大量证据并不支持在成人和儿童膳食指南中区分正脂和低脂乳制品食品。主要侧重于减少高能量、低营养的食物(西方饮食中反式脂肪酸的主要来源),而不是乳制品中的脂肪含量的策略,更有可能有益于人们的心血管健康。未来的研究需要更好地了解常脂和低脂乳制品食品在健康饮食模式中的地位。
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来源期刊
CiteScore
12.40
自引率
4.20%
发文量
332
审稿时长
38 days
期刊介绍: American Journal of Clinical Nutrition is recognized as the most highly rated peer-reviewed, primary research journal in nutrition and dietetics.It focuses on publishing the latest research on various topics in nutrition, including but not limited to obesity, vitamins and minerals, nutrition and disease, and energy metabolism. Purpose: The purpose of AJCN is to: Publish original research studies relevant to human and clinical nutrition. Consider well-controlled clinical studies describing scientific mechanisms, efficacy, and safety of dietary interventions in the context of disease prevention or health benefits. Encourage public health and epidemiologic studies relevant to human nutrition. Promote innovative investigations of nutritional questions employing epigenetic, genomic, proteomic, and metabolomic approaches. Include solicited editorials, book reviews, solicited or unsolicited review articles, invited controversy position papers, and letters to the Editor related to prior AJCN articles. Peer Review Process: All submitted material with scientific content undergoes peer review by the Editors or their designees before acceptance for publication.
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