The Interplay Between Personality and Clinical Syndromes in Eating Disorders: Implications for Personalized Treatment

IF 3.2 3区心理学 Q1 PSYCHOLOGY, CLINICAL Clinical psychology & psychotherapy Pub Date : 2025-03-17 DOI:10.1002/cpp.70061

Paolo Meneguzzo, Francesca Buscaglia, Anna Pillan, Enrica Bucci, Alice Garolla, Anna Marzotto, Chiara Cazzola, Roberta Castegnaro, Elisa Bonello, Patrizia Todisco

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Abstract

Introduction

Eating disorders (EDs) are complex and multifactorial conditions with significant impacts on both physical and mental health. Despite advances in treatment, relapse rates remain high, highlighting the need for improved predictive models for treatment outcomes. This study aims to examine the role of personality traits and clinical syndromes, as assessed by the Millon Clinical Multiaxial Inventory-III (MCMI-III), in predicting treatment outcomes for individuals with EDs.

Methods

A retrospective evaluation was conducted on 149 women diagnosed with EDs, receiving inpatient treatment at the Eating Disorder Unit of Casa di Cura Villa Margherita-KOS (Arcugnano-Vicenza) between 2020 and 2024. Participants completed the MCMI-III at treatment initiation, with the Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA) administered at baseline and discharge.

Results

Regression analyses revealed that maladaptive personality traits (avoidant, dependent and histrionic) and clinical syndromes such as major depression were significant negative predictors of treatment response. In contrast, post-traumatic stress emerged as a positive predictor of improvement. Specific personality and clinical patterns were associated with changes in symptomatology, including reductions in eating concerns, shape concerns and clinical impairment. However, not all dimensions were predictive of treatment outcomes.

Conclusion

This study underscores the importance of personalized treatment approaches that account for both personality traits and clinical syndromes in individuals with EDs. Future research should explore how these factors interact over time and inform tailored therapeutic strategies, particularly for those with comorbid traits or disorders.

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引言饮食失调症（ED）是一种复杂的多因素疾病，对身心健康都有重大影响。尽管在治疗方面取得了进展，但复发率仍然很高，这凸显了改进治疗结果预测模型的必要性。本研究旨在通过米隆临床多轴问卷-III（MCMI-III）的评估，研究人格特质和临床综合征在预测 ED 患者治疗效果方面的作用。方法对 2020 年至 2024 年期间在 Casa di Cura Villa Margherita-KOS（Arcugnano-Vicenza）饮食失调科接受住院治疗的 149 名被诊断患有 ED 的女性进行了回顾性评估。参与者在开始治疗时填写 MCMI-III，并在基线和出院时进行饮食失调检查问卷 (EDE-Q) 和临床损害评估 (CIA)。结果回归分析显示，适应不良型人格特质（回避型、依赖型和组织型）和临床综合征（如重度抑郁症）对治疗反应有显著的负面预测作用。相比之下，创伤后应激反应则是预测病情改善的积极因素。特定的人格和临床模式与症状的变化有关，包括饮食问题、外形问题和临床损害的减少。然而，并非所有方面都能预测治疗结果。结论本研究强调了个性化治疗方法的重要性，这种方法既考虑到了 ED 患者的人格特征，也考虑到了他们的临床综合征。未来的研究应探索这些因素如何随着时间的推移而相互作用，并为定制的治疗策略提供依据，尤其是针对那些有合并特征或障碍的患者。

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来源期刊

Clinical psychology & psychotherapy PSYCHOLOGY, CLINICAL-

CiteScore

6.30

自引率

5.60%

发文量

106

期刊介绍： Clinical Psychology & Psychotherapy aims to keep clinical psychologists and psychotherapists up to date with new developments in their fields. The Journal will provide an integrative impetus both between theory and practice and between different orientations within clinical psychology and psychotherapy. Clinical Psychology & Psychotherapy will be a forum in which practitioners can present their wealth of expertise and innovations in order to make these available to a wider audience. Equally, the Journal will contain reports from researchers who want to address a larger clinical audience with clinically relevant issues and clinically valid research.