Joslaine Jacumazo, Lilian Fernanda Martins do Amaral, Pierina Alexandra Martinez Huamani, Natalia Mello da Silva, Natalia Brasil Posselt Costa, Rilton Alves de Freitas
{"title":"Lignin nanoparticles as sustainable stabilizers for pickering emulsions","authors":"Joslaine Jacumazo, Lilian Fernanda Martins do Amaral, Pierina Alexandra Martinez Huamani, Natalia Mello da Silva, Natalia Brasil Posselt Costa, Rilton Alves de Freitas","doi":"10.1016/j.molliq.2025.127393","DOIUrl":null,"url":null,"abstract":"<div><div>Lignin is an abundant aromatic biopolymer known for its low toxicity, biodegradability, and renewable sourcing. In this manuscript, lignin was processed into nanoparticles to exploit its emulsifying potential. The antisolvent precipitation method was used to synthesize lignin nanoparticles (LigNPs), which were characterized for their size, morphology, stability, and cytotoxicity. The chemical structure of lignin was confirmed through HSQC-NMR, revealing no significant changes after fractionation. LigNPs exhibited colloidal stability over 90 days, maintaining stable apparent hydrodynamic diameters and negative zeta potentials, indicating stability due to electrostatic repulsion. Macroscopic and microscopic analyses confirmed their effectiveness in stabilizing emulsions, with densely packed interfaces at higher nanoparticles concentrations (0.100 % w v<sup>−1</sup>). The addition of salt destabilized the emulsions, highlighting the role of electrostatic interactions in stabilization. Confocal microscopy revealed complete particle coverage at the oil droplet interface, forming a stable barrier against coalescence. The emulsions exhibited promising long-term stability, minimal creaming, and good biocompatibility. These findings underscore the potential of LigNPs as cost-effective, eco-friendly alternatives in various industries, including pharmaceuticals, cosmetics, and food, supporting lignin valorization within a circular economy framework.</div></div>","PeriodicalId":371,"journal":{"name":"Journal of Molecular Liquids","volume":"427 ","pages":"Article 127393"},"PeriodicalIF":5.2000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Molecular Liquids","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167732225005604","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/14 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Lignin is an abundant aromatic biopolymer known for its low toxicity, biodegradability, and renewable sourcing. In this manuscript, lignin was processed into nanoparticles to exploit its emulsifying potential. The antisolvent precipitation method was used to synthesize lignin nanoparticles (LigNPs), which were characterized for their size, morphology, stability, and cytotoxicity. The chemical structure of lignin was confirmed through HSQC-NMR, revealing no significant changes after fractionation. LigNPs exhibited colloidal stability over 90 days, maintaining stable apparent hydrodynamic diameters and negative zeta potentials, indicating stability due to electrostatic repulsion. Macroscopic and microscopic analyses confirmed their effectiveness in stabilizing emulsions, with densely packed interfaces at higher nanoparticles concentrations (0.100 % w v−1). The addition of salt destabilized the emulsions, highlighting the role of electrostatic interactions in stabilization. Confocal microscopy revealed complete particle coverage at the oil droplet interface, forming a stable barrier against coalescence. The emulsions exhibited promising long-term stability, minimal creaming, and good biocompatibility. These findings underscore the potential of LigNPs as cost-effective, eco-friendly alternatives in various industries, including pharmaceuticals, cosmetics, and food, supporting lignin valorization within a circular economy framework.
木质素是一种丰富的芳香生物聚合物，以其低毒、可生物降解和可再生来源而闻名。在这篇论文中，木质素被加工成纳米颗粒，以利用其乳化潜力。采用反溶剂沉淀法合成了木质素纳米颗粒（LigNPs），并对其大小、形态、稳定性和细胞毒性进行了表征。通过HSQC-NMR确认木质素的化学结构，分离后木质素的化学结构无明显变化。在90天内，LigNPs表现出胶体稳定性，保持稳定的表观流体动力直径和负zeta电位，表明静电斥力的稳定性。宏观和微观分析证实了它们在稳定乳状液方面的有效性，在较高的纳米颗粒浓度（0.100% w v−1）下具有致密的界面。盐的加入使乳液不稳定，突出了静电相互作用在稳定中的作用。共聚焦显微镜显示，在油滴界面上完全覆盖了颗粒，形成了一个稳定的防止聚结的屏障。乳剂表现出良好的长期稳定性、最小的乳化和良好的生物相容性。这些发现强调了木质素作为各种行业（包括制药、化妆品和食品）具有成本效益、环保替代品的潜力，支持木质素在循环经济框架内的增值。
期刊介绍：
The journal includes papers in the following areas:
– Simple organic liquids and mixtures
– Ionic liquids
– Surfactant solutions (including micelles and vesicles) and liquid interfaces
– Colloidal solutions and nanoparticles
– Thermotropic and lyotropic liquid crystals
– Ferrofluids
– Water, aqueous solutions and other hydrogen-bonded liquids
– Lubricants, polymer solutions and melts
– Molten metals and salts
– Phase transitions and critical phenomena in liquids and confined fluids
– Self assembly in complex liquids.– Biomolecules in solution
The emphasis is on the molecular (or microscopic) understanding of particular liquids or liquid systems, especially concerning structure, dynamics and intermolecular forces. The experimental techniques used may include:
– Conventional spectroscopy (mid-IR and far-IR, Raman, NMR, etc.)
– Non-linear optics and time resolved spectroscopy (psec, fsec, asec, ISRS, etc.)
– Light scattering (Rayleigh, Brillouin, PCS, etc.)
– Dielectric relaxation
– X-ray and neutron scattering and diffraction.
Experimental studies, computer simulations (MD or MC) and analytical theory will be considered for publication; papers just reporting experimental results that do not contribute to the understanding of the fundamentals of molecular and ionic liquids will not be accepted. Only papers of a non-routine nature and advancing the field will be considered for publication.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
