[Analysis of the current status and related factors of antiviral treatment for chronic hepatitis B virus infection in rural communities of Zhangqiu District, Jinan City].

Abstract

Objective: To investigate the current status and related factors of antiviral treatment for chronic hepatitis B virus (HBV) infection in rural communities in China. Methods: In 2023, 866 chronic HBV-infected individuals from rural communities in Zhangqiu District, Jinan City, were included in the study. Basic information, disease status and antiviral treatment conditions of the infected individuals were collected through questionnaires, specimen collection and laboratory tests. Univariate and multivariate logistic regression were used to analyze the related factors of the antiviral treatment rate of those who met the indications for hepatitis B antiviral treatment. Results: The median age (Q₁, Q₃) of subjects was 56 (48, 66) years old, among which 436 (50.4%) were males. There were 712 (82.2%) individuals who met the indications for hepatitis B antiviral treatment, and 110 individuals received antiviral treatment with a rate of 15.5%. Multivariate logistic regression analysis showed that compared with males, families with an average monthly income per capita of <1 000 yuan, no alcohol consumption, no smoking, and a family history of HBV infection, females (OR=4.66, 95%CI: 2.88-7.53), families with an average monthly income per capita of 1 000-1 999 yuan (OR=1.64, 95%CI: 1.00-2.68) and ≥2 000 yuan (OR=2.78, 95%CI: 1.54-5.03), alcohol consumption (OR=6.42, 95%CI: 2.80-14.7), smoking (OR=1.98, 95%CI: 1.04-3.77), and no family history of HBV infection (OR=1.90, 95%CI: 1.16-3.09) had a lower antiviral treatment rate for chronic HBV infection. Conclusion: The antiviral treatment rate of chronic HBV-infected individuals in rural communities of Zhangqiu District, Jinan City is low, and the related factors are female, high monthly income per capita, alcohol consumption, smoking, and no family history of HBV infection.