A new insecticidal sesquiterpene from a mangrove endophytic fungus Aspergillus strain sp. GXNU R1.

IF 1.6 3区 化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2025-04-04 DOI:10.1080/14786419.2025.2487687
Xiongtao Yu, Meijing Tan, Xianglong Bo, Zhifan Lin, Jinwei Chen, Xishan Huang, Jiguo Huang
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Abstract

An undescribed sesquiterpene guxinusocapsa A (1), featuring a unique 5/7/6 tricyclic skeleton, and three known compounds (2-4) was isolated from the mangrove endophytic fungus Aspergillus sp. GXNU R1. These isolates were established primarily through NMR data analysis. The new structure's absolute configuration of 1 was identified by its single-crystal X-ray diffraction analysis. Compound 1 showed strong activity towards the Asian citrus psyllid (Diaphorina citri) with 95% lethal at 1000 mg/kg.

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从红树林内生真菌曲霉菌株sp. GXNU R1中分离出一种新的杀虫倍半萜。
从红树林内生真菌Aspergillus sp. GXNU R1中分离到一种未描述的倍半萜guxinusocapsa A(1),具有独特的5/7/6三环骨架和3个已知化合物(2-4)。这些分离物主要通过核磁共振数据分析得到。通过单晶x射线衍射分析,确定了新结构的绝对构型为1。化合物1对柑桔木虱(Diaphorina citri)有较强的杀伤活性,在1000 mg/kg时杀伤率达95%。
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来源期刊
Natural Product Research
Natural Product Research 化学-医药化学
CiteScore
5.10
自引率
9.10%
发文量
605
审稿时长
2.1 months
期刊介绍: The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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