Elisangela Oliveria Desiderio, Valdo Soares Martins Júnior, Alisson Samuel Portes Caldeira, Tânia Maria de Almeida Alves, Juliana Pimenta Cruz, Thallyta Maria Vieira, Viviane Oliveira Vasconcelos, Eduardo Robson Duarte
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引用次数: 0
Abstract
Plant-derived compound emerges as alternatives to integrated control of Aedes aegypti, the main transmitter of Chikungunya, Dengue, Zika virus. The effects of Magonia pubescens A. St.-Hill extracts on Ae. aegypti larval development were assessed. Four in vitro assays analysed the insecticidal potential (% larval mortality) of aqueous and ethanolic (EE) extracts of leaves and seeds. The extracts were analysed using UHPLC-MS/MS. By comparing to data from three databases, 12 compounds from different classes were identified in the EE, including coumarins, phenolic acids, polyphenols, and flavonoids. The EE from the leaves was the most effective, with an LC90 of 0.262 mg/mL. Morphological alterations were observed in larvae exposed to the extracts, showing epithelial walls with extravasation of intestinal contents. These findings highlight the effectiveness of M. pubescens extract as a bioinsecticidal agent against Ae. aegypti larvae.
Magonia pubescens A. St.-Hil.(无患子科）种子和叶提取物对埃及伊蚊的杀幼虫活性。
植物衍生化合物成为综合控制埃及伊蚊的替代方案，埃及伊蚊是基孔肯雅热、登革热、寨卡病毒的主要传播媒介。短毛magnonia A. . hill提取物对伊蚊的防治作用。评估埃及伊蚊幼虫发育情况。四项体外试验分析了叶片和种子的水提取物和乙醇提取物的杀虫潜力（幼虫死亡率）。采用UHPLC-MS/MS对提取物进行分析。通过比较3个数据库的数据，鉴定出12种不同类别的化合物，包括香豆素、酚酸、多酚和类黄酮。以叶中提取的EE效果最好，LC90为0.262 mg/mL。暴露于提取物的幼虫形态发生改变，显示肠内容物外溢的上皮壁。研究结果表明，短毛霉提取物对伊蚊具有较好的生物杀虫效果。蚊幼虫。
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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