Serum cobalt-activated acylase as a marker of transplantable leukemia in mice.

Polskie archiwum weterynaryjne Pub Date : 1988-01-01
K A Sobiech, J A Madej
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Abstract

The activity of cobalt-activated acylase was determined in the serum of mice with transplantable leukemia (P 388, L 1210 standard, L 1210/ara-C, L 1210/CH3-G, plasmocytoma ADJPC-5, lymphoma AKSL-4 and natural leukemia in mice NZB). A statistically significant increase in enzyme activity in all leukemias except lymphatic leukemia has been demonstrated. The results suggest possibility of using the enzymatic measurement as a marker of transplantable leukemia in mice.

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血清钴活化酰化酶作为小鼠可移植白血病的标志物。
测定了移植性白血病(p388、l1210标准、l1210 /ara-C、l1210 /CH3-G、浆细胞瘤ADJPC-5、淋巴瘤AKSL-4和自然白血病小鼠NZB)血清中钴活化酰化酶的活性。除淋巴白血病外,所有白血病的酶活性均有统计学意义的增加。这一结果提示了将酶促测定作为小鼠可移植白血病标志物的可能性。
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