Interstitial foam cells in the nephrotic syndrome belong to the monocyte/macrophage lineage.

F Nolasco, J S Cameron, R Reuben, B Hartley, F Carvalho, R A Coelho
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Abstract

Interstitial foam cells are occasionally seen in patients with the nephrotic syndrome. In a group of patients with the nephrotic syndrome we were able to demonstrate that these cells express markers characteristic of the monocyte/macrophage lineage. Their presence was related to the previous duration of proteinuria, but they had no apparent influence on the subsequent evolution of renal function. The mechanisms leading to their presence are unknown.

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肾病综合征的间质泡沫细胞属于单核/巨噬细胞谱系。
间质泡沫细胞偶尔见于肾病综合征患者。在一组肾病综合征患者中,我们能够证明这些细胞表达单核/巨噬细胞谱系特征的标记物。它们的存在与先前蛋白尿的持续时间有关,但它们对随后的肾功能演变没有明显影响。导致它们存在的机制尚不清楚。
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