Changes in body compartments on different types of haemodialysis.

M García, M Carrera, C Piera, R Deulofeu, X Company, J M Pons, J Montoliu, J Setoain, L Revert
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Abstract

Changes in plasma volume (PV), extracellular volume (ECV) and intracellular volume (ICV) were studied in seven patients on conventional haemodialysis (HD) and in six patients on stable hypertonic HD. Weight loss and ultrafiltration were similar in both groups. Before HD the spaces of 125RISA (PV), 35SO4Na2 (ECV) and 3H2) (total body water, TBW) were simultaneously determined ICV = TBW - ECV. At the end of HD the space of 35SO4Na2 was again tested. PV and ECV diminished more on conventional HD than on hypertonic HD, whereas ICV increased on conventional HD and decreased on hypertonic HD. The handling of plasma osmolality during HD is an effective method for modifying transcompartmental body fluid shifts in HD by distributing weight loss between intracellular and extracellular spaces allowing for a better maintenance of plasma volume.

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不同类型血液透析的体室变化。
研究了7例常规血液透析(HD)患者和6例稳定型高渗血液透析(HD)患者血浆体积(PV)、细胞外体积(ECV)和细胞内体积(ICV)的变化。两组的减重和超滤效果相似。HD前同时测定125RISA (PV)、35SO4Na2 (ECV)和3H2 (total body water, TBW)的空间,ICV = TBW - ECV。在HD结束时,再次测试35SO4Na2的空间。常规HD组的PV和ECV比高渗HD组降低更多,而常规HD组的ICV增加,高渗HD组的ICV减少。在HD期间处理血浆渗透压是一种有效的方法,通过在细胞内和细胞外空间之间分配体重减轻来改变HD患者的跨室体液转移,从而更好地维持血浆体积。
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