[Informative aspects of interaction between regulatory peptides and cellular membranes].

Fiziologicheskiĭ zhurnal Pub Date : 1993-09-01
V R Mohylevych, H V Ostrovska, V K Rybalćhenko
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Abstract

The mechanism of interaction between regulatory peptides (RP) and plasma membranes of target cells were discussed from the positions of the informative theory. Quantity of information in molecules of RP in the solution and the coefficient of excess in the binding of the RP with the cell plasma membrane were calculated. Participation of different membrane components in the informative signal transduction was characterized. Proceeding from the results of own experiments and data from literature the role of the membrane lipid matrix in interaction between RP and a cell was analyzed. A scheme of regulation of the RP information effect on the cell is suggested.

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[调节肽与细胞膜相互作用的信息性方面]。
从信息论的角度探讨了调控肽与靶细胞质膜相互作用的机理。计算了溶液中RP分子的信息量和RP与细胞膜结合的过量系数。表征了不同膜组分在信息信号转导中的参与。从自己的实验结果和文献资料出发,分析了膜脂基质在RP与细胞相互作用中的作用。提出了一种调节RP信息对细胞影响的方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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[Effect of antibodies specific to sarcolemma of cardiomyocytes in activity of 5-nucleotidase in rats]. [Effect of small doses of pituitrin on electrocardiography of ischemia in the experiment]. [Effect of intracerebral injections of somatostatin and neurotensin on motor functions in seizure]. [Informative aspects of interaction between regulatory peptides and cellular membranes]. [Pathogenesis of atherosclerosis in diabetes mellitus. The role of insulin resistance and hyperinsulinemia].
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