[Atrial natriuretic factor in endocrine pathology].

Fiziologicheskiĭ zhurnal Pub Date : 1993-09-01
S T Zubkova, E V Epshteĭn, V A Oleĭnik, G N Terekhova
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Abstract

The content of basal immunoreactive atrial natriuretic hormone (ANH) in the venous blood plasma was studied in patients with various types of endocrine hypertension (Conn's syndrome, pheochromocytoma, neuroendocrine form of hypothalamic syndrome, diabetes mellitus) and diffuse toxic goiter. Increase of the ANH level was revealed in patients with primary aldosteronism, diabetes mellitus and hypertension, as well as with decompensated thyrotoxicosis and pronounced cardiac changes. In patients with neuroendocrine pattern of the hypothalamic syndrome the ANH level remained unchanged, in those with pheochromocytoma it decreased.

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[内分泌病理中的房利钠因子]。
研究了不同类型内分泌高血压(康氏综合征、嗜铬细胞瘤、神经内分泌型下丘脑综合征、糖尿病)和弥漫性中毒性甲状腺肿患者静脉血中基础免疫反应性心房利钠激素(ANH)的含量。原发性醛固酮增多症、糖尿病、高血压、失代偿性甲状腺毒症及明显心脏病变患者均可见ANH水平升高。在下丘脑综合征的神经内分泌模式患者中,ANH水平保持不变,在嗜铬细胞瘤患者中,ANH水平下降。
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