[Changes in hypophyseal-ovarian axis hormone levels in the first days after central nervous system surgery].

Abstract

The authors examined the FSH, LH, prolactin, oestradiol and progesterone levels during the perioperative period in 14 women, mean age 35.7 years, who were subjected to intracranial operations. They found that during the first postoperative days the FSH level (p < or = 0.01), LH level (p < or = 0.01) and oestradiol level (p < or = 0.05) declined, while the progesterone and prolactin level do not change significantly. This is consistent with data in the literature on transient hypogonadotropic hypogonadism after head injuries or after operations and injuries of other organs. The disorder is only of a short-term character and does not lead to serious impairment of the menstrual cycle.