L Fialová, I Malbohan, L Mikulíková, Z Lacinová, Z Hájek
{"title":"[SP1 serum levels in pregnancy with Rh isoimmunization].","authors":"L Fialová, I Malbohan, L Mikulíková, Z Lacinová, Z Hájek","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The authors examined in 37 pregnant women hospitalized on account of Rh incompatibility during the second and third trimester 71 serum specimens for levels of trophoblast specific beta 1-glycoprotein (SP1), using the method of simple radial immunodiffusion. In the group of 16 women with Rh incompatibility whose pregnancy terminated by delivery of a normal neonate, in 22% the SP1 levels were higher than 1.5 x the median value for the given gestation week (MoM). In 17 pregnancies where the foetus suffered from haemolytic disease the SP1 levels were higher than 1.5 MoM in 45% of the examined foetuses. Markedly elevated SP1 levels of 2.3 and 2.4 MoM were recorded in two pregnancies with hydrops of the foetus.</p>","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 2","pages":"57-60"},"PeriodicalIF":0.0000,"publicationDate":"1993-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ceskoslovenska gynekologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The authors examined in 37 pregnant women hospitalized on account of Rh incompatibility during the second and third trimester 71 serum specimens for levels of trophoblast specific beta 1-glycoprotein (SP1), using the method of simple radial immunodiffusion. In the group of 16 women with Rh incompatibility whose pregnancy terminated by delivery of a normal neonate, in 22% the SP1 levels were higher than 1.5 x the median value for the given gestation week (MoM). In 17 pregnancies where the foetus suffered from haemolytic disease the SP1 levels were higher than 1.5 MoM in 45% of the examined foetuses. Markedly elevated SP1 levels of 2.3 and 2.4 MoM were recorded in two pregnancies with hydrops of the foetus.
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