M Iu Alesina, O O Sukachova, S Ts Zilberman, O O Konovalenko, G O Nesterenko, O M Beskrovnyĭ
{"title":"[State of the endocrine system in rats of various ages under immobilization stress and influence of adaptogenic biomos].","authors":"M Iu Alesina, O O Sukachova, S Ts Zilberman, O O Konovalenko, G O Nesterenko, O M Beskrovnyĭ","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of administration, of BIOMOS-VJ on the concentration of thyroxine, triiodothyronine, corticosterone, insulin and glucose in the blood serum of the normal state and under conditions of immobilization stress of young and aged Wistar's rats has been studied. The experiments have shown that the administration of preparation prevents the appearance of disturbances in endocrine system of the organism typical of stress such as a decrease in concentration of thyroid hormones and insulin and also a considerable increase in corticosterone and glucose concentration in the blood serum. On the basis of the results indicating the influence of BIOMOS-VJ on the endocrine system of young and aged Wistar's rats it is assumed that this preparation has gero-protected properties.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"78-83"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fiziologicheskiĭ zhurnal","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The effect of administration, of BIOMOS-VJ on the concentration of thyroxine, triiodothyronine, corticosterone, insulin and glucose in the blood serum of the normal state and under conditions of immobilization stress of young and aged Wistar's rats has been studied. The experiments have shown that the administration of preparation prevents the appearance of disturbances in endocrine system of the organism typical of stress such as a decrease in concentration of thyroid hormones and insulin and also a considerable increase in corticosterone and glucose concentration in the blood serum. On the basis of the results indicating the influence of BIOMOS-VJ on the endocrine system of young and aged Wistar's rats it is assumed that this preparation has gero-protected properties.
研究了给药bio - os - vj对正常状态和固定应激条件下幼龄和老年Wistar大鼠血清中甲状腺素、三碘甲状腺原氨酸、皮质酮、胰岛素和葡萄糖浓度的影响。实验表明,制剂的施用可以防止机体内分泌系统出现典型的应激紊乱,如甲状腺激素和胰岛素浓度的降低以及血清中皮质酮和葡萄糖浓度的显著增加。基于对年轻和老年Wistar大鼠内分泌系统影响的结果,我们认为该制剂具有老年保护作用。