[Comparison of the effectiveness of oil and water solutions of alpha-tocopherol as radiation protection agent].

Fiziologicheskiĭ zhurnal Pub Date : 1993-03-01
A V Paranich, S M Oleksieiev, M B Tarabrin, Zh Godonu, G V Savchenko, M Traore
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引用次数: 0

Abstract

The change in alpha-tocopherol content (as an index of the antioxidative organism system mobilization) in the brain, liver, muscles and heart of rats prior to and after total gamma-irradiation with lethal dose has been studied. Prior to the irradiation alpha-tocopheryl-acetate (oil solution), alpha-tocopheryl-phosphate dipotassium salt (water solution), gammaphos (prepared WR 2721, water solution) were introduced into rats. It is shown that water-soluble form of vitamin E is more effective than gammaphos and much more efficient than oil form of alpha-tocopherol.

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[α -生育酚油、水溶液防辐射效果的比较]。
研究了全致死剂量γ辐照前后大鼠脑、肝、肌肉和心脏中α -生育酚含量(作为抗氧化生物体系统动员的指标)的变化。在辐照前,将α -生育酚乙酸酯(油溶液)、α -生育酚磷酸二钾盐(水溶液)、γ多酚(制备的WR 2721,水溶液)引入大鼠体内。研究表明,水溶性维生素E比γ -酚更有效,比油形式的α -生育酚更有效。
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