[Tumors of the anterior skull base. Effects of perioperative imaging on adjuvant radiotherapy planning].

J V Anton, J Schultze, W Gstöttner, C Matula
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Abstract

Objectives: Treatment of anterior skull base tumours is still considered being a major challenge for all involved disciplines. Surgical management, complications, as well as the role of imaging for multimodality treatment options should be evaluated critically.

Patients and methods: 57 patients underwent interdisciplinary one step trans-basal approaches for resection of benign and malignant anterior fossa tumours. Beside assessment of surgical results and perioperative morbidity, in 13 patients with malignant tumours perioperative imaging was evaluated with regard to further possible radio-oncological treatment options.

Results: Applying trans-basal approaches radical tumour resection could be achieved in all cases independent of tumor-size (diameter 12-114 mm). Permanent postoperative complications (until 6 months postoperatively) were found in 4 cases (7%), transient complications in 7 cases (12.3%). Evaluation of perioperative imaging showed a heterogen use of different imaging modalities and revealed lack of standardization, hampering further planning of radiation therapy.

Conclusion: Treatment of anterior skull base tumours requires a maximum level of standardization of perioperative imaging, to grant a successful surgical and radio-oncological interdisciplinary patient management.

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[前颅底肿瘤。围手术期影像学对辅助放疗计划的影响[j]。
目的:前颅底肿瘤的治疗仍然被认为是所有相关学科的主要挑战。手术处理,并发症,以及多模式治疗方案的成像的作用应严格评估。患者和方法:57例患者采用跨学科一步跨基底入路行良性和恶性前窝肿瘤切除术。除了评估手术结果和围手术期发病率外,对13例恶性肿瘤患者的围手术期影像学进行了评估,以进一步考虑可能的放射肿瘤学治疗方案。结果:不论肿瘤大小(直径12- 114mm),均可采用经基底入路根治性切除。术后6个月永久性并发症4例(7%),短暂性并发症7例(12.3%)。围手术期影像学评估显示不同影像学方式使用的异质性,显示缺乏标准化,阻碍了放射治疗的进一步规划。结论:前颅底肿瘤的治疗需要最大程度的围手术期影像学标准化,以确保成功的外科和放射肿瘤学跨学科患者管理。
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