Developing Public Health Interventions with Xylitol for the US and US-Associated Territories and States.

Peter Milgrom, Marilynn Rothen, Linda Milgrom
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Abstract

This paper examines how the limited exposure of the professional dental community in the United States to the potential caries reduction benefits of xylitol, and the absence of vehicles for xylitol that could be recommended in private practice settings or applied in public health programs, has retarded xylitol's adoption. Few papers appeared in the English language literature prior to the last two decades but now a greater number are appearing. Current work at the University of Washington has led to a series of randomized controlled trials more clearly establishing dosing and frequency guidelines and increased interest in use of xylitol products for caries prevention. Steps to develop effective alternative vehicles for the delivery of xylitol particularly useful for young children and institutional settings in America, and their bioequivalency, are explored.

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发展木糖醇对美国和美国相关领土和州的公共卫生干预。
本文研究了美国专业牙科社区对木糖醇潜在的减龋益处的有限接触,以及木糖醇在私人执业环境或公共卫生计划中可推荐的载体的缺乏,如何阻碍了木糖醇的采用。在过去的二十年里,很少有论文出现在英语语言文学中,但现在出现了更多的论文。华盛顿大学目前的工作已经导致了一系列随机对照试验,更清楚地建立了剂量和频率指南,并增加了对木糖醇产品用于预防龋齿的兴趣。步骤,以开发有效的替代车辆木糖醇输送特别适用于幼儿和机构设置在美国,他们的生物等效性进行了探讨。
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[Orthognathic surgery]. Developing Public Health Interventions with Xylitol for the US and US-Associated Territories and States. Compliance with Xylitol and Sorbitol Chewing Gum Regimens in Clinical Trials. On the Acquisition of Periodontopathic Bacteria by Children from Mothers: A Randomized Double-Masked Placebo-Controlled Trial in Bauru, Brazil. [Development of caries in deciduous teeth and the presence of Streptococcus mutans in the mothers' saliva].
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