[Accuracy evaluation of diagnostic test in laboratory].

中国疫苗和免疫 Pub Date : 2009-10-01
Shou-Jun Zhao, Shuang Zhang, Feng Wang
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引用次数: 0

Abstract

The theory and application of ROC curve are briefly introduced in this paper. Three main ROC curve related indices, area under curve (AUC), partial area under curve (pAUC), and sensitivity at a particular false-positive-rate (1-specificity) [Se(FPR=e)], are used to analyze a real data of five hepatitis B surface agent kits with calculated steps and explanation, including the bootstrap method for statistical inference of these indices.

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[实验室诊断试验的准确性评价]。
简要介绍了ROC曲线的原理及其应用。采用曲线下面积(AUC)、曲线下部分面积(pAUC)和特定假阳性率敏感性(1-特异性)[Se(FPR=e)]这三个主要的ROC曲线相关指标,对5种乙肝表面药物试剂盒的真实数据进行了分析,并给出了计算步骤和解释,包括对这些指标进行统计推断的bootstrap方法。
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