[Resistance and serotype of 123 strains of Streptococcus pneumoniae].

中国疫苗和免疫 Pub Date : 2010-02-01
Hong-Yu Ren, Xiao-Lei Wang, Ma-Chao Li
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Abstract

Objective: To investigate antibiotic resistance and the prevalence of serotype of Streptococcus pneumoniae.

Methods: Totally 123 strains of S. pneumoniae were collected to test the susceptibility of 6 antibiotics by K-B method according to the standard of CLIS. Serotyping of S. pneumoniae was performed by using quelling reaction.

Results: Among 123 strains of S. pneumoniae, all strains (100%) were resistant to AZM. There were 65.04%, 78.05%, 19.51%, 0.81%, 0% of S. pneumoniae were resistant against the MH, SXT, C, RA, OFX respectively. 11 serotypes were involved in 123 strains. The prevalent serogroup were 6, 14, 15, 19 and 23.5 strains were unable to serotype. The multi-resistant strains of S. pneumoniae included in serogroup 6 and 19.

Conclusion: The antibiotic resistance of S. pneumoniae is very serious. Most of them are multi-resistant strains. The prevalent serogroup, especially of the multi-resistant strains, are 6 and 19 serogroup.

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[123株肺炎链球菌耐药性及血清型分析]。
目的:了解肺炎链球菌耐药情况及血清型流行情况。方法:收集肺炎链球菌123株,按照CLIS标准,采用K-B法对6种抗生素进行药敏试验。采用平息反应法对肺炎链球菌进行血清分型。结果:123株肺炎链球菌均对AZM耐药(100%)。肺炎链球菌对MH、SXT、C、RA、OFX的耐药率分别为65.04%、78.05%、19.51%、0.81%、0%。123株涉及11种血清型。不能分型的株有6株、14株、15株、19株和23.5株。肺炎链球菌多重耐药菌株包括血清6组和血清19组。结论:肺炎链球菌耐药情况严重。其中大多数是多重耐药菌株。流行的血清群,特别是多重耐药菌株,是6和19血清群。
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