[Case-control study on epidemiology factors of measles in Zhejiang Province in 2008].

中国疫苗和免疫 Pub Date : 2010-02-01
En-fu Chen, Han-Qing He, Qian Li
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Abstract

Objective: In order to analysis the main factors of measles prevalence in 2008, and to provide evidence for establishing scientific strategies on measles elimination.

Methods: 1:1 matched case-control study was conducted in 3 cities, and the conditional logistic regression was used to analyse the risk factor of measles.

Results: 358 matched pairs (716 objects) were investigated. Floating population, hospital exposure were related factors by single factor conditional logistic regression, and multiple factor conditional logistic regression showed the odds ratio of hospital exposure was 2.33 (P < 0.05). Meanwhile, non-immunization was the main possible risk factor in the subjects aged from 8 months to 2 years, which odds ratios for measles was 65.29 (P < 0.05).

Conclusion: Hospital exposure, floating population and existing of non-immunization were the main factor for measles prevalence. It is necesarry to strengthen supervision and education for reducing the exposure opportunities. To perfect the floating population management and ensure the high coverage of 2 dose measles vaccine in children are suggested.

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2008年浙江省麻疹流行病学因素的病例对照研究
目的:分析2008年麻疹流行的主要影响因素,为制定科学的消除麻疹策略提供依据。方法:在3个城市进行1:1匹配病例对照研究,采用条件logistic回归分析麻疹危险因素。结果:共调查了358对(716个对象)。单因素条件logistic回归分析显示,流动人口、医院暴露与住院暴露的比值比为2.33 (P < 0.05)。未接种疫苗是8个月~ 2岁儿童发生麻疹的主要危险因素,麻疹的比值比为65.29 (P < 0.05)。结论:医院暴露、流动人口和未免疫接种是影响麻疹流行的主要因素。要加强监管和教育,减少暴露机会。建议完善流动人口管理,确保儿童麻疹2剂疫苗的高覆盖率。
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