[Analysis on influenza antibodies detection rate and infected recently among infants].

中国疫苗和免疫 Pub Date : 2009-12-01
Feng-jiao Hu, Hong-xia Ni, Su-li Jiao
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Abstract

Objective: To understand the status of infants infected with influenza viruses after switch over of dominant strain in the summer of 2006.

Methods: Two groups of infants serum were collected and to be detected the antibodies of influenza viruses which the infants experienced two peaks of influenza A H1N1 circulation in the age of 3-4 and 10-11 months old and the infants only experience one circulation in 5-6 months old.

Results: The antibody of influenza A H1N1 viruses was 31.47% in the infants who experience two circulations in 3-4 months and 10-11 months old and was 26.42% which only experience circulation in the 5-6 months old. There were no significant difference between 2 groups (chi2 = 1.207, P > 0.05).

Conclusion: The group of 13 months age of infants were rarely infected influenza virus in the first time exposure at the age of < or =4 months due to maternal antibodies protection. Whenas, the group of 8 months age who were exposed at the age of > or =5 months, were more easier infected the influenza virus than the group of 13 months age in the first time exposure at the age of < or =4 months.

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婴儿流感抗体检出率及近期感染情况分析
目的:了解2006年夏季流感病毒优势株转换后的婴幼儿感染情况。方法:采集两组婴儿血清,检测流感病毒抗体,其中3 ~ 4月龄和10 ~ 11月龄出现两次甲型H1N1流感循环高峰,5 ~ 6月龄仅出现一次流感循环。结果:3 ~ 4月龄和10 ~ 11月龄两次循环的婴儿甲型H1N1流感病毒抗体阳性率为31.47%,5 ~ 6月龄只循环的婴儿抗体阳性率为26.42%。两组间比较差异无统计学意义(χ 2 = 1.207, P > 0.05)。结论:13月龄组婴儿在<或=4月龄时首次接触流感病毒感染的情况极少,主要是由于母体抗体的保护作用。8月龄>或=5月龄暴露组在<或=4月龄首次暴露时比13月龄组更容易感染流感病毒。
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