[Analysis on coverage of hepatitis A vaccine among pre-school children in Shandong province].

中国疫苗和免疫 Pub Date : 2009-12-01
Bing-yu Yan, Li Zhang, Li-zhi Song
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Abstract

Objective: To reveal the hepatitis A vaccine (HepA) coverage among pre-school children in Shandong province before Hepatitis A vaccine was introduced to the EPI and to provide evidence for improving the strategy for hepatitis A control.

Methods: A cross-section survey was conducted among children aged between 2 and 6 years old in Shandong province in March 2008. The study population was selected by random sampling method and HepA immunization history was obtained by immunization record or recall.

Results: 78.90% had received one dose of HepA at least. The coverage rate decreased with age and the differences in three age groups were statistically significant (chi2 = 11.54, P = 0.02). The coverage rates among the boys and girls were 77.67% and 80.30% respectively, the difference was not significantly (chi2 = 1.17, P = 0.28). The HepA coverage rates among the children living in the eastern areas and in the richer areas were higher than the centrale and western areas and poverty areas, the difference has statistic significance (chi2 = 27.25, 58.17, P < 0.001).

Conclusion: The HepA routine immunization should be enhanced, especially in central and western areas and a HepA catch-up campaign should be conducted among the pre-school children in Shandong province.

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山东省学龄前儿童甲肝疫苗接种率分析
目的:了解甲型肝炎疫苗未纳入计划免疫前山东省学龄前儿童甲型肝炎疫苗(HepA)的接种率,为完善甲型肝炎控制策略提供依据。方法:2008年3月对山东省2 ~ 6岁儿童进行横断面调查。研究人群采用随机抽样方法,通过免疫记录或召回获得HepA免疫史。结果:78.90%的患者至少接受过一次HepA治疗。覆盖率随年龄增长而下降,3个年龄组间差异有统计学意义(χ 2 = 11.54, P = 0.02)。男孩和女孩的覆盖率分别为77.67%和80.30%,差异无统计学意义(χ 2 = 1.17, P = 0.28)。东部地区和富裕地区儿童HepA覆盖率高于中西部地区和贫困地区,差异有统计学意义(χ 2 = 27.25、58.17,P < 0.001)。结论:应加强HepA常规免疫,特别是在中西部地区,并在山东省学龄前儿童中开展HepA追赶运动。
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