[Fragility Fractures in Hemodialysis Patients. "Classical" osteoporosis in dialysis patients.]

Abstract

Previous studies demonstrated that patients undergoing chronic dialysis therapy showed several times higher risks for hip fracture compared to those of healthy subjects. Their bone tissue would be vulnerable because of the bone loss and poor quality. In addition, volume and strength of the muscle are decreased and the ratio of sarcopenia or frailty is increased among these patients, accordingly leading to higher risks for falls and bone fractures. Considering the pathophysiology of bone fracture in dialysis patients, it is a matter of course that one wonders how effective recently developed medicine for"classical" osteoporosis is. However, evidence to guide us is currently lacking. Therefore, it is crucial for us to construct evidence by observational and interventional studies.