[Fragility Fractures in Hemodialysis Patients. Abnormalities of osteocyte functions in chronic kidney disease.]

Clinical calcium Pub Date : 2018-01-01 DOI:CliCa180810811086
Yoshiko Iwasaki
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Abstract

Increased fracture incidence and ectopic calcifications which are accompanied with mineral metabolic disorders are well seen in dialysis patients. The role of bone in chronic kidney disease patients including dialysis has been investigated in clinical findings and experimental examinations. The abnormalities of osteocyte function have been pointed to as an active inducer of pathology of a deregulated endocrine organ.

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血液透析患者脆性骨折。慢性肾脏疾病中骨细胞功能异常[j]。
骨折发生率增高和异位钙化伴矿物质代谢紊乱在透析患者中很常见。骨在包括透析在内的慢性肾脏病患者中的作用已经在临床表现和实验检查中进行了研究。骨细胞功能异常已被认为是内分泌器官失调病理的积极诱因。
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